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Review
. 2025 Mar 21;15(7):476.
doi: 10.3390/nano15070476.

Nanoparticles as Strategies for Modulating the Host's Response in Periodontitis Treatment

Antoaneta Mlachkova  1 , Velitchka Dosseva-Panova  1 , Hristina Maynalovska  1 , Zdravka Pashova-Tasseva  1
Affiliations
Review

Nanoparticles as Strategies for Modulating the Host's Response in Periodontitis Treatment

Antoaneta Mlachkova et al. Nanomaterials (Basel). .

Abstract

Periodontitis is a widespread disease, associated with challenges both in its diagnosis and in selecting from various therapeutic approaches, which do not always yield the expected success. This literature review was conducted to explore diverse therapeutic approaches, especially those focused on nanotechnologies, and their potential contribution to the successful modulation of the host's response. The effects of the existing microbial diversity and the imbalance of key microbial species in contributing to the progression and worsening of the host's response in periodontitis are well known. It is essential to understand the role of a well-structured treatment plan for periodontitis, providing opportunities for new research and innovative treatment strategies aimed at reducing the impact of periodontitis on oral and overall systemic health. This will be beneficial for dental professionals, enabling them to effectively prevent and treat periodontitis, ultimately improving the overall health and well-being of patients.

Keywords: host response; innovative strategies; nanoparticles; periodontitis; therapeutic approaches.

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Conflict of interest statement

The authors declare no conflicts of interest.

Figures

Figure 1
Figure 1
Effects of the most used metal nanoparticles in periodontology.
Figure 2
Figure 2
Nanotherapeutics in periodontal treatment plans.
See this image and copyright information in PMC

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