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. 2025 Aug;46(4):615-637.
doi: 10.1007/s10935-025-00835-0. Epub 2025 Apr 11.

Lifestyle Modification Programs and Interventions on Prediabetes in Saudi Arabia: A Systematic Scoping Review

Nahla Mohammed Bawazeer  1 , Abeer Salman Alzaben  1 , Elizabeth Dodge  2 , Amelia J Baker  3 , Nada Benajiba  4 , Basil H Aboul-Enein  5   6
Affiliations

Lifestyle Modification Programs and Interventions on Prediabetes in Saudi Arabia: A Systematic Scoping Review

Nahla Mohammed Bawazeer et al. J Prev (2022). 2025 Aug.

Abstract

Prediabetes is characterized by elevated blood glucose and glycated hemoglobin levels (HbA1c) that remain below the diagnostic threshold for type 2 diabetes. It increases the risk of diabetes, all-cause mortality, and chronic diseases. Saudi Arabia has one of the highest global diabetes rates. This review evaluates interventions targeting prediabetes in Saudi Arabia and provides recommendations based on their effectiveness. A systematic scoping review was conducted across 12 databases for intervention studies published through March 2024. Study quality was assessed using the Academy of Nutrition and Dietetics Evidence Analysis Library Manual Quality Criteria. Six lifestyle intervention studies in Saudi Arabia, lasting from six months to over a year, were analyzed. All demonstrated good quality with minimal selection bias. Intervention groups showed significant improvements in metabolic syndrome components, fasting glucose, Homeostatic Model Assessment of Insulin Resistance, and HbA1c. One study reported prediabetes reversal and type 2 diabetes remission following lifestyle modifications. Multi-center interventions combining education, counseling, and physical activity were more effective than general advice alone in improving metabolic outcomes. Lifestyle modifications are an effective first-line approach for prediabetes management. In addition to the health benefits associated with improving glycemic control, lifestyle modification has the potential to reduce individual and public healthcare costs associated with prediabetes. This review supports the efficacy of lifestyle modification programs, conducted in Saudi Arabia, in controlling or reversing prediabetes.

Keywords: Intervention; Lifestyle intervention; Middle East; Prediabetes; Public health; Saudi Arabia.

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Conflict of interest statement

Declarations. Conflict of interest: The authors declare no conflict of interest. Ethical approval: No ethical oversight was found to be necessary for this review and, therefore, no institutional review board was obtained.

References

    1. Abu-Ras, W., & Laird, L. (2011). How muslim and non-muslim chaplains serve muslim patients? Does the interfaith chaplaincy model have room for muslims’ experiences? Journal of Religion and Health, 50(1), 46–61. https://doi.org/10.1007/s10943-010-9357-4 - DOI - PubMed
    1. Abuyassin, B., & Laher, I. (2015). Obesity-linked diabetes in the Arab world: A review. Eastern Mediterranean Health Journal., 21(6), 420–439. https://doi.org/10.26719/2015.21.420 - DOI - PubMed
    1. Academy of Nutrition and Dietetics Evidence Analysis Library. (2022). Evidence Analysis Manual. Retrieved Apr 12th from https://www.andeal.org/evidence-analysis-manual
    1. Afifi, R. M., Omar, S. R., & El Raggal, A. A. (2015). A community screening plan for the prevalence of some chronic diseases in specified adult populations in Saudi Arabia: 1- prediabetes and diabetes mellitus. International Journal of Diabetes in Developing Countries, 35(3), 149–156. https://doi.org/10.1007/s13410-013-0189-0 - DOI
    1. Al Amri, T., Bahijri, S., Al-Raddadi, R., Ajabnoor, G., Al Ahmadi, J., Jambi, H., Borai, A., & Tuomilehto, J. (2019). The association between prediabetes and dyslipidemia among attendants of primary care Health Centers in Jeddah, Saudi Arabia. Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy, 12, 2735–2743. https://doi.org/10.2147/DMSO.S233717 - DOI - PubMed

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