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. 2025 Feb 19;7(1):13.
doi: 10.1186/s42494-025-00205-7.

The use of AI in epilepsy and its applications for people with intellectual disabilities: commentary

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The use of AI in epilepsy and its applications for people with intellectual disabilities: commentary

Madison Milne-Ives et al. Acta Epileptol. .

Abstract

Epilepsy is one of the most common neurological disorders, affecting more than 50 million people worldwide. Management is particularly complex in individuals with intellectual disabilities, who are at a much higher risk of having severe seizures compared to the general population. People with intellectual disabilities are regularly excluded from epilepsy research, despite having significantly higher risks of negative health outcomes and early mortality. Recent advances in artificial intelligence (AI) have shown great potential in improving the diagnosis, monitoring, and management of epilepsy. Machine learning techniques have been used in analysing electroencephalography data for efficient seizure detection and prediction, as well as individualised treatment, which facilitates timely and customised intervention for individuals with epilepsy. Research and implementation of AI-based solutions for people with intellectual disabilities and epilepsy still remains limited due to a lack of accessible long-term clinical data for model training, difficulties in communicating with people with intellectual disabilities, and ethical challenges in ensuring the safety of the AI systems for this population. This paper presents an overview of recent AI applications in epilepsy and for people with intellectual disabilities, highlighting key challenges and the necessity of including people with intellectual disabilities in research on AI and epilepsy, and potential strategies to promote the development and use of AI applications for this vulnerable population. Given the prevalence and consequences associated with epilepsy in people with intellectual disabilities, the application of AI in epilepsy care has the potential to have a significant positive impact. To achieve this impact and to avoid increasing existing health inequity, there is an urgent need for greater inclusion of people with intellectual disabilities in research around the application of AI to epilepsy care and management.

Keywords: Artificial intelligence; Epilepsy; Intellectual disability; Personalised treatment.

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Conflict of interest statement

Ethics approval and consent to participate: Not applicable. Consent for publication: Not applicable. Competing interests: EM and GPW are guest editors for the Artificial Intelligence in Epilepsy: Advances in Diagnosis and Treatment collection in Acta Epileptologica who were not involved in the journal’s review of or decisions related to this manuscript. The other authors declare that they have no competing interests.

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