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Review
. 2025 Mar 27;14(7):2305.
doi: 10.3390/jcm14072305.

Management of SARS-CoV-2 Infection-Clinical Practice Guidelines of the Polish Association of Epidemiologists and Infectiologists, for 2025

Robert Flisiak  1 , Jerzy Jaroszewicz  2 , Dorota Kozielewicz  3 , Ernest Kuchar  4 , Miłosz Parczewski  5 , Małgorzata Pawłowska  3 , Anna Piekarska  6 , Piotr Rzymski  7 , Krzysztof Simon  8 , Krzysztof Tomasiewicz  9 , Dorota Zarębska-Michaluk  10
Affiliations
Review

Management of SARS-CoV-2 Infection-Clinical Practice Guidelines of the Polish Association of Epidemiologists and Infectiologists, for 2025

Robert Flisiak et al. J Clin Med. .

Abstract

The first Polish recommendations for the management of COVID-19 were published by the Polish Society of Epidemiologists and Infectiologists (PTEiLChZ) on 31 March 2020, and the last three years ago. The emergence of new SARS-CoV-2 variants, a different course of the disease, as well as new knowledge about therapies and vaccines, requires updating diagnostic, therapeutic, and prophylactic guidelines. Despite the reduction in the threat associated with COVID-19, there is a risk of another epidemic caused by coronaviruses, which was an additional reason for developing a new version of the guidelines. In preparing these recommendations, the Delphi method was used, reaching a consensus after three survey cycles. Compared to the 2022 version, the names of the individual stages of the disease have been changed, adapting them to the realities of clinical practice, and attention was paid to the differences observed in immunosuppressed patients and in children. Some previously recommended drugs have been discontinued, including monoclonal antibodies. In addition, general principles of vaccination were presented, as well as issues related to the post-COVID syndrome.

Keywords: COVID-19; SARS-CoV-2; diagnostics; prevention; therapy.

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Conflict of interest statement

Grants, advisory, or/and honoraria—R.F.: Gilead, Moderna, MSD, Novavax, Pfizer, Roche; J.J.: Gilead, Moderna, MSD, Pfizer, Roche; D.K.: declares no conflicts of interest; E.K.: Pfizer, Moderna, Novavax, MSD; M.Par: Pfizer, Roche; M.Paw.: Gilead, MSD, Pfizer, Roche; A.P.: Gilead, Pfizer; P.R.: Moderna, Pfizer; K.S.: Gilead, MSD, Roche, Red Hill Biopharma; K.T.: AstraZeneca, Gilead, Pfizer, Roche; D.Z.M.: Gilead, Pfizer, Roche.

Figures

Figure 1
Figure 1
Recommended treatment regimen for COVID-19.
See this image and copyright information in PMC

References

    1. WHO COVID-19 Dashboard. [(accessed on 2 March 2025)]. Available online: https://data.who.int/dashboards/covid19/cases.
    1. Flisiak R., Horban A., Jaroszewicz J., Kozielewicz D., Pawłowska M., Parczewski M., Piekarska A., Simon K., Tomasiewicz K., Zarębska-Michaluk D. Management of SARS-CoV-2 infection: Recommendations of the Polish Association of Epidemiologists and Infectiologists as of March 31, 2020. Pol. Arch. Intern. Med. 2020;130:352–357. - PubMed
    1. Flisiak R., Horban A., Jaroszewicz J., Kozielewicz D., Pawłowska M., Parczewski M., Piekarska A., Simon K., Tomasiewicz K., Zarębska-Michaluk D. Management of SARS-CoV-2 infection: Recommendations of the Polish Association of Epidemiologists and Infectiologists. Annex no. 1 as of June 8, 2020. Pol. Arch. Intern. Med. 2020;130:557–558. - PubMed
    1. Flisiak R., Parczewski M., Horban A., Jaroszewicz J., Kozielewicz D., Pawłowska M., Piekarska A., Simon K., Tomasiewicz K., Zarębska-Michaluk D. Management of SARS-CoV-2 infection: Recommendations of the Polish Association of Epidemiologists and Infectiologists. Annex no. 2 as of October 13, 2020. Pol. Arch. Intern. Med. 2020;130:915–918. - PubMed
    1. Flisiak R., Horban A., Jaroszewicz J., Kozielewicz D., Mastalerz-Migas A., Owczuk R., Parczewski M., Pawłowska M., Piekarska A., Simon K., et al. Management of SARS-CoV-2 infection: Recommendations of the Polish Association of Epidemiologists and Infectiologists as of April 26, 2021. Pol. Arch. Intern. Med. 2021;131:487–496. - PubMed

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