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. 2025 Apr 6;14(7):2492.
doi: 10.3390/jcm14072492.

Long-Term Excellent Clinical Outcomes, High Survivorship, and Low Osteoarthritis Progression in Lateral Unicompartmental Knee Arthroplasty: A 10-Year Minimum Follow-Up

Affiliations

Long-Term Excellent Clinical Outcomes, High Survivorship, and Low Osteoarthritis Progression in Lateral Unicompartmental Knee Arthroplasty: A 10-Year Minimum Follow-Up

Matteo Marullo et al. J Clin Med. .

Abstract

Background: The literature on the long-term outcomes of lateral unicompartmental knee arthroplasty (UKA) remains limited due to the lower prevalence of lateral osteoarthritis (OA) and the technical challenges of the procedure. This study aimed to assess the long-term clinical outcomes, implant survivorship, and OA progression in patients undergoing lateral UKA with a minimum follow-up of 10 years. Methods: This retrospective study analyzed 96 lateral UKAs from 2001 to 2013 using a cemented, fixed-bearing implant. Patients with at least 10 years of follow-up were included. Clinical outcomes were measured using range of motion (ROM), a pain visual analog scale (VAS), Knee Society Scores (KSSs), and the Forgotten Joint Score (FJS). Implant survivorship was assessed using a Kaplan-Meier analysis, while OA progression in the medial compartment was evaluated radiographically. Results: At a mean follow-up of 14.5 years, implant survivorship was 94.7%, with five revisions primarily due to OA progression. Significant improvements were observed in ROM, VAS, and KSS (p < 0.01). An increase in the Kellgren-Lawrence grade in the medial compartment was reported in 47.9% of patients. Conclusions: Lateral UKA provides excellent long-term outcomes, demonstrating high survivorship, significant functional improvement, and high patient satisfaction.

Keywords: ACL-sparing knee replacement; knee replacement; lateral unicompartmental knee replacement; mininvasive surgery; partial knee replacement; unicompartmental knee replacement.

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Conflict of interest statement

SR is a paid consultant for Zimmer Biomet, Warsaw, IN. The other authors declare no conflicts of interest.

Figures

Figure 1
Figure 1
CONSORT diagram of this study.
Figure 2
Figure 2
Survival function of lateral UKA; mo, months.
Figure 3
Figure 3
Kellgren–Lawrence grade in medial compartment. (Left) Preoperative grade. (Right) Grade at last follow-up (mean 14.5 years).
Figure 4
Figure 4
Pie chart representing patients’ satisfaction.

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