A Narrative Review of Quercetin's Role as a Bioactive Compound in Female Reproductive Disorders

Abstract

Lifestyle, nutrition, and metabolic status are central to maintaining women's reproductive health. With the rising prevalence of infertility, the need for effective strategies to preserve and enhance women's reproductive well-being has become increasingly urgent. Quercetin, a plant-derived polyphenol, has attracted growing interest for its potential to support reproductive health, regulate the hormonal balance, and improve fertility. This narrative review examines Quercetin's role in women's reproductive health and delineates its possible mechanisms of action in female reproductive system disorders, including polycystic ovary syndrome, recurrent miscarriage, and cervical, ovarian, and endometrial cancer (EC). By highlighting the biological pathways through which quercetin may exert its effects, this article underscores the need for further research and clinical trials to validate its therapeutic potential and its applications as a bioactive compound in foods aimed at enhancing women's reproductive health.

Keywords: female reproductive disorders; gynecological cancers; polycystic ovary syndrome; pregnancy loss; quercetin.

Figure 1

Effect of Quercetin on PCOS and pregnancy loss: potential mechanisms by which Quercetin alleviates PCOS symptoms and improves pregnancy outcomes.