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. 1985 May;67(1):3-9.
doi: 10.1007/BF00220979.

The role of the cell cycle in differentiation of the cellular slime mould Dictyostelium discoideum

P T Sharpe, D J Watts

The role of the cell cycle in differentiation of the cellular slime mould Dictyostelium discoideum

P T Sharpe et al. Mol Cell Biochem. 1985 May.

Abstract

During development and differentiation of the cellular slime mould Dictyostelium discoideum there appears to be a relationship between the cell cycle and cell fate: amoebae halted in G2 phase during early development differentiate into spores whereas stalk cells are formed from amoebae halted in G1 phase. It is proposed that this is because a major effect of the cell cycle is to generate heterogeneity in the cell surface properties of the developing amoebae.

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