Rapid clinical and transcriptomic response to anifrolumab in refractory anti-TIF1γ-positive juvenile dermatomyositis

Affiliations

¹ Department of Pediatrics, CHU Sainte-Justine, Université de Montréal, Montreal, QC, Canada; Pôle de Pathologies Rhumatismales Systémiques et Inflammatoires (RUMA), Institut de Recherche Expérimentale et Clinique (IREC), Université Catholique de Louvain, Brussels, Belgium.
² Department of Pediatrics, CHU Sainte-Justine, Université de Montréal, Montreal, QC, Canada; CHU Sainte-Justine Research Center, Université de Montréal, Montreal, QC, Canada.
³ Department of Pathology, CHU Sainte-Justine, Université de Montréal, Montreal, QC, Canada.
⁴ Centre de recherche Azrieli, Montreal, QC, Canada.
⁵ Department of medicine, CHU Sainte-Justine, Université de Montréal, Montreal, QC, Canada.
⁶ Department of Pediatrics, CHU Sainte-Justine, Université de Montréal, Montreal, QC, Canada.
⁷ Department of Pediatrics, Department of microbiology, immunology and infectious diseases, CHU Sainte-Justine Azrieli Research Center, Université de Montréal, Montreal, QC, Canada.
⁸ Department of Pediatrics, CHU Sainte-Justine, Université de Montréal, Montreal, QC, Canada. Electronic address: marie-paule.morin@umontreal.ca.

Clément Triaille et al. Ann Rheum Dis. 2025 Jun.

. 2025 Jun;84(6):1052-1054.

doi: 10.1016/j.ard.2025.02.002. Epub 2025 Apr 11.

¹ Department of Pediatrics, CHU Sainte-Justine, Université de Montréal, Montreal, QC, Canada; Pôle de Pathologies Rhumatismales Systémiques et Inflammatoires (RUMA), Institut de Recherche Expérimentale et Clinique (IREC), Université Catholique de Louvain, Brussels, Belgium.
² Department of Pediatrics, CHU Sainte-Justine, Université de Montréal, Montreal, QC, Canada; CHU Sainte-Justine Research Center, Université de Montréal, Montreal, QC, Canada.
³ Department of Pathology, CHU Sainte-Justine, Université de Montréal, Montreal, QC, Canada.
⁴ Centre de recherche Azrieli, Montreal, QC, Canada.
⁵ Department of medicine, CHU Sainte-Justine, Université de Montréal, Montreal, QC, Canada.
⁶ Department of Pediatrics, CHU Sainte-Justine, Université de Montréal, Montreal, QC, Canada.
⁷ Department of Pediatrics, Department of microbiology, immunology and infectious diseases, CHU Sainte-Justine Azrieli Research Center, Université de Montréal, Montreal, QC, Canada.
⁸ Department of Pediatrics, CHU Sainte-Justine, Université de Montréal, Montreal, QC, Canada. Electronic address: marie-paule.morin@umontreal.ca.

No abstract available

Conflict of interest statement

Competing interests The authors have no competing interest to disclose in relationship with this manuscript.