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. 2025 Apr 13;24(1):23.
doi: 10.1186/s12991-025-00558-w.

Prevalence and comorbidity of attention deficit hyperactivity disorder in Chinese school-attending students aged 6-16: a national survey

Affiliations

Prevalence and comorbidity of attention deficit hyperactivity disorder in Chinese school-attending students aged 6-16: a national survey

Jingran Liu et al. Ann Gen Psychiatry. .

Abstract

Background: Attention deficit hyperactivity disorder (ADHD) is a prevalent neurodevelopmental disorder. Despite its significance, no large-scale epidemiological study assessing ADHD, and its associated comorbidities in children and adolescents has been conducted in China.

Methods: Within a national epidemiological survey of 73,992 children and adolescents aged between 6 and 16 in China, we used the CBCL, MINI-KID, and DSM-IV to identify ADHD and its comorbid conditions. Chi-square tests were utilized to compare the prevalence estimates across varied age and sex groups.

Results: The overall ADHD prevalence was estimated at 6.4% (95% CI: 6.2-7.0%). Broken down by subtypes, ADHD-I had a prevalence of 3.9%, ADHD-C was at 1.7%, and ADHD-H was at 0.9%. Boys and the younger age bracket recorded higher prevalence rates for ADHD and its subtypes (p < 0.001). Among ADHD-diagnosed individuals, 53% exhibited at least one comorbid psychiatric disorder. Oppositional defiant disorder/conduct disorder (ODD/CD) was the most prevalent comorbidity for ADHD-C and ADHD-H, at 58%, while anxiety disorders, at 17%, were predominant among ADHD-I cases. ODD/CD was notably higher among younger subjects (p < 0.001). In contrast, anxiety disorders were more frequent in older children and in girls (p < 0.001). Tic disorders showed a higher prevalence in younger boys, whereas mood and substance use disorders were more common in older boys (p < 0.001).

Conclusions: ADHD is a common neurodevelopmental disorder with high comorbidity rates that vary substantially across subtypes, age, and sex. These clinical heterogeneities complicate management and highlight the need for tailored interventions.

Keywords: ADHD; Children and adolescents; Comorbidity; Prevalence.

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Conflict of interest statement

Declarations. Ethics approval and consent to participate: All participants and their parents provided informed consent prior to participation in the study. The study adhered to the principles of the Declaration of Helsinki and received approval from the Ethics Committee of Anding Hospital, Capital Medical University (Project identification code: 2012BAI01B02). Competing interests: The authors declare no competing interests.

Figures

Fig. 1
Fig. 1
The flowchart for the procedures of the survey Note: CBCL: Child Behavior Checklist; MINI-Kid: Mini International Neuropsychiatric Interview for Children and Adolescents; ADHD: Attention deficit hyperactivity disorder; ADHD-I: the predominantly inattentive type; ADHD-H: the predominantly hyperactive-impulsive type; ADHD-C: the combined type
Fig. 2
Fig. 2
The trend with age for the prevalence of ADHD and its subtypes Note: ADHD: attention deficit hyperactivity disorder; ADHD-I: the predominantly inattentive type; ADHD-H: the predominantly hyperactive-impulsive type; ADHD-C: the combined type
Fig. 3
Fig. 3
The comorbidity of ADHD and its subtypes Note: ADHD: attention deficit hyperactivity disorder; ADHD-I: the predominantly inattentive type; ADHD-H: the predominantly hyperactive-impulsive type; ADHD-C: the combined type; ODD: oppositional defiant disorder; CD: conduct disorder

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