Reversible chronic cerebellar ataxia after phenytoin intoxication: possible role of cerebellum in cognitive thought

Abstract

Reversible chronic cerebellar ataxia followed phenytoin treatment in two epileptic women. Cerebellar ataxia in both patients and axonal polyneuropathy in one patient were improved after administration of thiamine alone or with folate. In one patient, some specific behavioral functions improved. However, recovery could have been spontaneous.