Advantages and challenges of using arterial spin labelling MRI to monitor cerebral blood flow in multi-centre clinical trials of neurodegenerative disease: Comment
- PMID: 40224382
- PMCID: PMC11986485
- DOI: 10.1016/j.cccb.2025.100382
Advantages and challenges of using arterial spin labelling MRI to monitor cerebral blood flow in multi-centre clinical trials of neurodegenerative disease: Comment
Abstract
•More research should be performed on how to deal with variances in MRI machines and imaging settings across several locations. Using higher resolution imaging techniques or creating statistical methods to adjust results to account for variances in MRI machines between sites can help to improve the study's accuracy.•More research should be performed on how to deal with variances in MRI machines and imaging settings across several locations.•Using higher resolution imaging techniques or creating statistical methods to adjust results to account for variances in MRI machines between sites can help to improve the study's accuracy.
© 2025 The Author(s).
Conflict of interest statement
The authors declare no conflict.
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References
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- Jarutyte L., Petr J., Turner N., Kehoe P.G., Mutsaerts H.J., Thomas D.L. Advantages and challenges of using arterial spin labelling MRI to monitor cerebral blood flow in multi-centre clinical trials of neurodegenerative disease: experience from the RADAR study. Cereb Circ Cogn Behav. 2025 Jan 1;8 - PMC - PubMed
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