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Review
. 2025 Mar 6:2025:6330337.
doi: 10.1155/drp/6330337. eCollection 2025.

Nail Polishes: A Review on Composition, Presence of Toxic Components, and Inadequate Labeling

Aislana Cole de Paula  1 , Fabrício Uliana  1 , Eloi Alves da Silva Filho  1 , Priscilla Paiva Luz  1
Affiliations
Review

Nail Polishes: A Review on Composition, Presence of Toxic Components, and Inadequate Labeling

Aislana Cole de Paula et al. Dermatol Res Pract. .

Abstract

Nail polishes were developed in 1920, and since 1940, it has been known that these cosmetics contain toxic and sensitizing components. Over the years, nail polishes have undergone several changes in their formulation to avoid this problem, but new components have also been considered toxic and allergenic. The growing demand for gel nails has also been highlighted in cases of allergy to (meth)acrylates, and the biggest concern that was previously related to the presence of toluene sulfonamide-formaldehyde resin (TSFR) in traditional nail polish formulations is now also part of (meth)acrylate-based cosmetics. The beautification caused by nail polish is the main factor behind its constant use throughout the world, but studies have demonstrated its use for other purposes, such as treating fungal diseases, sun protection factor in cancer patients, and as a possible ally in forensic area. This review brings the beginning of the discovery of nail polish and its trajectory to the present day, including its effects on health and its inadequate labeling. Therefore, it is extremely important that legislation monitors the composition of nail cosmetics and that new formulations are studied to make them safe for health and the environment.

Keywords: cosmetics; formulation; nail polish; polymers; toxic components.

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Conflict of interest statement

The authors declare no conflicts of interest.

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