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. 1985 Jul 11;13(13):4613-22.
doi: 10.1093/nar/13.13.4613.

A highly polymorphic region 3' to the human type II collagen gene

N G Stoker, K S Cheah, J R Griffin, F M Pope, E Solomon
Free PMC article

A highly polymorphic region 3' to the human type II collagen gene

N G Stoker et al. Nucleic Acids Res. .
Free PMC article

Abstract

We have characterised a highly polymorphic region 1.3kb downstream of the human Type II collagen gene. It consists of a highly AT-rich tandem repetitive region (minisatellite) approximately 650bp long. Two alleles had been observed previously, differing in size by approximately 300bp. When this region was cloned from four unrelated individuals carrying the larger allele, DNA sequence data identified three alleles, suggesting far higher polymorphism than was originally supposed. This minisatellite was shown to be present in a single copy in the human genome, and to have arisen after the divergence of Old and New World monkeys.

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References

    1. Nature. 1977 Sep 22;269(5626):354-5 - PubMed
    1. J Med Genet. 1985 Jun;22(3):187-91 - PubMed
    1. Nucleic Acids Res. 1981 Sep 11;9(17):4213-24 - PubMed
    1. Nucleic Acids Res. 1981 Oct 10;9(19):5037-47 - PubMed
    1. Nature. 1982 Jan 7;295(5844):31-5 - PubMed

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