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. 2025 May;10(5):105064.
doi: 10.1016/j.esmoop.2025.105064. Epub 2025 Apr 14.

Systemic anticancer therapy near the end of life: an analysis of factors influencing treatment in advanced cancer patients

G Fornas  1 , J Montón-Bueno  1 , T Tortajada  1 , P Pérez  1 , A Guimerá  1 , D González  1 , B Iglesias  1 , A García  1 , N Grimalt  1 , M García  1 , I González-Barrallo  1 , A Viala-Monleón  1 , M J Molina-Garrido  1 , I Chirivella  1 , A Cervantes  2
Affiliations

Systemic anticancer therapy near the end of life: an analysis of factors influencing treatment in advanced cancer patients

G Fornas et al. ESMO Open. 2025 May.
No abstract available

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Figures

Figure 1
Figure 1
Lastreceived systemic anticancer treatment (SACT) and factors determining SACT near end of life. (A) Types of SACT received by patients (all patients, n = 1887). (B) Forest plot indicating an association between study variables and odds of receiving SACT within the last 30 days of life in patients who received SACT (n = 1304). CI, confidence interval; CTx, chemotherapy; HT, hormone therapy; ICI, immune checkpoint inhibitors; OR, odds ratio; SACT, systemic anticancer treatment; Trial, treatment in a clinical trial; TT, targeted therapy.
See this image and copyright information in PMC

References

    1. Le N.S., Zeybek A., Hackner K., et al. Systemic anticancer therapy near the end of life: an analysis of factors influencing treatment in advanced tumor disease. ESMO Open. 2024;9(9) - PMC - PubMed
    1. Cherny N.I., Nortjé N., Kelly R., et al. A taxonomy of the factors contributing to the overtreatment of cancer patients at the end of life. What is the problem? Why does it happen? How can it be addressed? ESMO Open. 2025;10(1) - PMC - PubMed
    1. Crawford G.B., Dzierżanowski T., Hauser K., et al. Care of the adult cancer patient at the end of life: ESMO Clinical Practice Guidelines. ESMO Open. 2021;6(4) - PMC - PubMed

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