Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2025 Apr 13;25(4):275-276.
doi: 10.1177/15357597251333157. eCollection 2025 Jul-Aug.

Channeling Seizure Control: Optogenetics in Human Brain Slices

Affiliations
Comment

Channeling Seizure Control: Optogenetics in Human Brain Slices

John D Rolston. Epilepsy Curr. .
No abstract available

PubMed Disclaimer

Comment on

  • Multimodal evaluation of network activity and optogenetic interventions in human hippocampal slices.
    Andrews JP, Geng J, Voitiuk K, Elliott MAT, Shin D, Robbins A, Spaeth A, Wang A, Li L, Solis D, Keefe MG, Sevetson JL, Rivera de Jesús JA, Donohue KC, Larson HH, Ehrlich D, Auguste KI, Salama S, Sohal V, Sharf T, Haussler D, Cadwell CR, Schaffer DV, Chang EF, Teodorescu M, Nowakowski TJ. Andrews JP, et al. Nat Neurosci. 2024 Dec;27(12):2487-2499. doi: 10.1038/s41593-024-01782-5. Epub 2024 Nov 15. Nat Neurosci. 2024. PMID: 39548326

References

    1. Sahel JA, Boulanger-Scemama E, Pagot C, Arleo A, Galluppi F, Martel JN, Esposti SD, Delaux A, de Saint Aubert JB, de Montleau C, Gutman E, Audo I, Duebel J, Picaud S, Dalkara D, Blouin L, Taiel M, Roska B. Partial recovery of visual function in a blind patient after optogenetic therapy. Nat Med. 2021;27(7):1223–1229. - PubMed
    1. Ledri M, Andersson M, Wickham J, Kokaia M. Optogenetics for controlling seizure circuits for translational approaches. Neurobiol Dis. 2023;184:106234. - PubMed
    1. Andersson M, Avaliani N, Svensson A, Wickham J, Pinborg LH, Jespersen B, Christiansen SH, Bengzon J, Woldbye DP, Kokaia M. Optogenetic control of human neurons in organotypic brain cultures. Sci Rep. 2016;6(1):24818. - PMC - PubMed
    1. Andrews JP, Geng J, Voitiuk K, et al. Multimodal evaluation of network activity and optogenetic interventions in human hippocampal slices. Nat Neurosci. 2024;27(12):2487–2499. - PMC - PubMed
    1. Zhao P, Ding X, Li L, Jiang G. A review of cell-type specific circuit mechanisms underlying epilepsy. Acta Epileptol. 2024;6(1):18. - PMC - PubMed

LinkOut - more resources