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. 2025 Jan 24;6(2):100041.
doi: 10.1016/j.acepjo.2024.100041. eCollection 2025 Apr.

Prehospital Blood Administration in Traumatic Hemorrhagic Shock

Affiliations

Prehospital Blood Administration in Traumatic Hemorrhagic Shock

Bryan McNeilly et al. J Am Coll Emerg Physicians Open. .

Abstract

Following the military's advancement of prehospital blood into the field, civilian prehospital blood programs are becoming more prevalent. However, there are significant differences between civilian and military prehospital operations that should be considered. Civilian prehospital systems also vary widely in terms of resources, transport times, and patient types. Given these variations and the logistical challenges associated with establishing a prehospital blood program, careful consideration of the state of the science is warranted. Although blood is the preferred fluid for patients in hemorrhagic shock, there have only been a few high-quality studies that have examined the efficacy of administering blood in the prehospital setting. Given the conflicting results of these studies, individual medical directors must determine whether the risk-benefit analysis for their system warrants establishing such a resource-intensive operation. Efforts to establish a prehospital blood program should not supersede attempts to optimize the fundamental components of trauma operations and management.

Keywords: EMS blood administration; blood products; fresh frozen plasma (FFP); management of traumatic hemorrhagic shock; packed red blood cells (pRBCs); prehospital blood program; whole blood.

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Conflict of interest statement

All authors have affirmed they have no conflicts of interest to declare.

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