doi: 10.1126/science.4023711.
Noninvasive study of high-energy phosphate metabolism in human heart by depth-resolved 31P NMR spectroscopy
- PMID: 4023711
- DOI: 10.1126/science.4023711
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Noninvasive study of high-energy phosphate metabolism in human heart by depth-resolved 31P NMR spectroscopy
Science.
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Abstract
Phosphorus-31 nuclear magnetic resonance (NMR) spectra showing the relative concentrations of high-energy phosphate metabolites have been recorded noninvasively from the human heart in vivo. Spectral data were spatially localized by combining a pulsed magnetic field gradient with surface NMR excitation-detection coils. The location of the selected spectral region was determined by conventional proton NMR imaging immediately before examination by phosphorus-31 NMR spectroscopy.
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