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. 2025 Jun;51(6):1192-1193.
doi: 10.1007/s00134-025-07867-4. Epub 2025 Apr 16.

Selection bias in the "TRAIN" randomized clinical trial: implications for meta-analyses

Ravi Garg  1
Affiliations

Selection bias in the "TRAIN" randomized clinical trial: implications for meta-analyses

Ravi Garg. Intensive Care Med. 2025 Jun.
No abstract available

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Conflict of interest statement

Declarations. Conflicts of interest: I report no conflicts of interest per ICMJE guidance.

References

    1. Blot P-L, Renaux M, Ayasse T et al (2025) Liberal vs. restrictive transfusion strategies for acute brain injury: a systematic review and frequentist-Bayesian meta-analysis. Intensive Care Med 51:353–363 - PubMed
    1. Taccone FS, Bittencourt CR, Møller K et al (2024) Restrictive vs liberal transfusion strategy in patients with acute brain injury: the TRAIN randomized clinical trial. JAMA 332(19):1623–1633 - PubMed - PMC
    1. Berger VW, Exner DV (1999) Detecting selection bias in randomized clinical trials. Control Clin Trials 20(4):319–327 - PubMed

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