Theological and Ethical Perspectives on Gene Editing and the Sanctity of Life: Rare Genetic Diseases in the Philippines as a Model

Abstract

This paper examines the interplay between the sacredness of life and gene editing in the context of rare genetic diseases. Rare genetic disorders caused by gene mutations often come with limited treatment options. Gene editing techniques present a promising solution by targeting and repairing defective genes. The discussion begins with an overview of the science behind gene editing and its potential applications in treating rare diseases, highlighting three specific genetic conditions affecting Filipinos. It then explores the ethical and theological dimensions of gene editing, emphasizing the Imago Dei doctrine, which underscores human dignity and moral responsibility as well as ethical principles in light of Christian virtues. A comparative analysis between therapeutic somatic gene editing and germline editing is highlighted in the discussions. Using the See-Judge-Act framework, the paper examines the potential of gene editing through the lens of Catholic Church's teachings on human dignity and offers practical insights for applying the theological and ethical considerations in addressing the therapeutic options for rare genetic diseases righteously.

Keywords: Germline gene editing; Human dignity; Imago Dei; Rare genetic diseases; Somatic gene editing.