Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Editorial
. 2025 May 6;14(9):e041733.
doi: 10.1161/JAHA.125.041733. Epub 2025 Apr 16.

Tenecteplase for Minor Stroke: Does Sex Matter?

Affiliations
Editorial

Tenecteplase for Minor Stroke: Does Sex Matter?

Beom Joon Kim. J Am Heart Assoc. .
No abstract available

Keywords: Editorials; TEMPO‐2; disparity; implementation; sex disparity; tenecteplase.

PubMed Disclaimer

Conflict of interest statement

None.

Comment on

References

    1. Seners P, Ben Hassen W, Lapergue B, Arquizan C, Heldner MR, Henon H, Perrin C, Strambo D, Cottier JP, Sablot D, et al. Prediction of early neurological deterioration in individuals with minor stroke and large vessel occlusion intended for intravenous thrombolysis alone. JAMA Neurol. 2021;78:321–328. doi: 10.1001/jamaneurol.2020.4557 - DOI - PMC - PubMed
    1. Powers WJ, Rabinstein AA, Ackerson T, Adeoye OM, Bambakidis NC, Becker K, Biller J, Brown M, Demaerschalk BM, Hoh B, et al. Guidelines for the early management of patients with acute ischemic stroke: 2019 update to the 2018 guidelines for the early management of acute ischemic stroke: a guideline for healthcare professionals from the American Heart Association/American Stroke Association. Stroke. 2019;50:e344–e418. doi: 10.1161/STR.0000000000000211 - DOI - PubMed
    1. Coutts SB, Ankolekar S, Appireddy R, Arenillas JF, Assis Z, Bailey P, Barber PA, Bazan R, Buck BH, Butcher KS, et al. Tenecteplase versus standard of care for minor ischaemic stroke with proven occlusion (TEMPO‐2): a randomised, open label, phase 3 superiority trial. Lancet. 2024;403:2597–2605. doi: 10.1016/S0140-6736(24)00921-8 - DOI - PubMed
    1. Chen HS, Cui Y, Zhou ZH, Zhang H, Wang LX, Wang WZ, Shen LY, Guo LY, Wang EQ, Wang RX, et al. Dual antiplatelet therapy vs alteplase for patients with minor nondisabling acute ischemic stroke: the ARAMIS randomized clinical trial. JAMA. 2023;329:2135–2144. doi: 10.1001/jama.2023.7827 - DOI - PMC - PubMed
    1. Khatri P, Kleindorfer DO, Devlin T, Sawyer RN Jr, Starr M, Mejilla J, Broderick J, Chatterjee A, Jauch EC, Levine SR, et al. Effect of alteplase vs aspirin on functional outcome for patients with acute ischemic stroke and minor nondisabling neurologic deficits: the PRISMS randomized clinical trial. JAMA. 2018;320:156–166. doi: 10.1001/jama.2018.8496 - DOI - PMC - PubMed

LinkOut - more resources