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Review
. 2025 Apr 15;27(4):493-499.
doi: 10.7499/j.issn.1008-8830.2411034.

[Research progress on risk factors for poor prognosis in pediatric non-esophageal eosinophilic gastrointestinal disorder]

[Article in Chinese]
Xiang-Hui Liu  1
Affiliations
Review

[Research progress on risk factors for poor prognosis in pediatric non-esophageal eosinophilic gastrointestinal disorder]

[Article in Chinese]
Xiang-Hui Liu. Zhongguo Dang Dai Er Ke Za Zhi. .

Abstract
in English, Chinese

Non-esophageal eosinophilic gastrointestinal disorder (non-EoE EGID) is a group of immune-mediated gastrointestinal diseases characterized by infiltration of eosinophils. Although most patients experience symptom relief after treatment, some still face the risk of persistent symptoms or relapse. Improving the prognosis for this subset of patients remains an urgent challenge. Identifying risk factors that affect the prognosis of non-EoE EGID and providing timely effective interventions are crucial for improving outcomes. This paper reviews the risk factors related to the prognosis of pediatric non-EoE EGID, including genetic factors, allergies, environmental factors, clinical characteristics, endoscopic findings, and pathological manifestations, with the aim of providing references for clinical decision-making.

非食管嗜酸粒细胞性胃肠道疾病（non-esophageal eosinophilic gastrointestinal disorder, non-EoE EGID）是一组以嗜酸性粒细胞浸润为特征的免疫介导的消化系统疾病。尽管多数患者在治疗后症状得到缓解，但仍有部分患者面临症状持续或复发的风险，改善这部分患者的预后是亟待解决的挑战，识别影响non-EoE EGID预后的危险因素并及时给予有效干预，对改善预后具有重要意义。该文对遗传因素、过敏、环境因素、临床特征、内镜表现、病理表现等与儿童non-EoE EGID预后相关的危险因素进行综述，以期为临床决策提供参考。.

Keywords: Child; Eosinophilic gastrointestinal disorder; Prognosis; Risk factor.

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Conflict of interest statement

所有作者声明无利益冲突。

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