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. 2025 Jun;51(6):1194-1195.
doi: 10.1007/s00134-025-07896-z. Epub 2025 Apr 17.

Selection bias in the "TRAIN" randomized clinical trial: implications for meta-analyses-Author's reply

Pierre-Louis Blot  1 , Maxime Renaux  1 , Timothée Ayasse  1 , Jean-Michel Constantin  1 , Rayan Braïk  2
Affiliations

Selection bias in the "TRAIN" randomized clinical trial: implications for meta-analyses-Author's reply

Pierre-Louis Blot et al. Intensive Care Med. 2025 Jun.
No abstract available

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Conflict of interest statement

Conflict of interest: The authors declare that they have no conflicts of interest related to this manuscript.

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References

    1. Blot P-L, Renaux M, Ayasse T et al (2025) Liberal vs. restrictive transfusion strategies for acute brain injury: a systematic review and frequentist-Bayesian meta-analysis. Intensive Care Med 51:353–363. https://doi.org/10.1007/s00134-025-07807-2 - DOI - PubMed
    1. Garg R (2025) Selection bias in the “TRAIN” randomized clinical trial: implications for meta-analyses. Intensive Care Med. https://doi.org/10.1007/s00134-025-07867-4 - DOI - PubMed
    1. Minozzi S, Dwan K, Borrelli F, Filippini G (2022) Reliability of the revised Cochrane risk-of-bias tool for randomised trials (RoB2) improved with the use of implementation instruction. J Clin Epidemiol 141:99–105. https://doi.org/10.1016/j.jclinepi.2021.09.021 - DOI - PubMed
    1. Yuan X, Zhang S, Wan J et al (2024) Efficacy of restrictive versus liberal transfusion strategies in patients with traumatic brain injury: a systematic review and meta-analysis of randomized controlled trials. Ann Intensive Care 14:177. https://doi.org/10.1186/s13613-024-01411-1 - DOI - PubMed - PMC
    1. Larcipretti ALL, Udoma-Udofa OC, Gomes FC et al (2025) Transfusion practices in traumatic brain injury: a systematic review and meta-analysis of randomized controlled trials. Crit Care Med. https://doi.org/10.1097/CCM.0000000000006585 - DOI - PubMed

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