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. 2025 Apr 1;8(4):e255721.
doi: 10.1001/jamanetworkopen.2025.5721.

Pneumococcal Hemolytic Uremic Syndrome in Children in Sweden

Affiliations

Pneumococcal Hemolytic Uremic Syndrome in Children in Sweden

Helena Hildenwall et al. JAMA Netw Open. .
No abstract available

Plain language summary

This cohort study of children in Sweden reviewed pneumococcal hemolytic uremic syndrome cases between 2009 and 2024 for incidence rates and serotype data.

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Conflict of interest statement

Conflict of Interest Disclosures: None reported.

Figures

Figure.
Figure.. Pneumococcal Hemolytic Uremic Syndrome Serotype Distribution
The vertical line indicates change from pneumococcal conjugate vaccine valence 13 (PCV13) to PCV10 in the Swedish National Immunization Program.

References

    1. Michael M, Bagga A, Sartain SE, Smith RJH. Haemolytic uraemic syndrome. Lancet. 2022;400(10364):1722-1740. doi:10.1016/S0140-6736(22)01202-8 - DOI - PubMed
    1. Constantinescu AR, Bitzan M, Weiss LS, et al. . Non-enteropathic hemolytic uremic syndrome: causes and short-term course. Am J Kidney Dis. 2004;43(6):976-982. doi:10.1053/j.ajkd.2004.02.010 - DOI - PubMed
    1. Makwana A, Sheppard C, Fry NK, Ladhani SN. Pneumococcal-related hemolytic uremic syndrome in the United Kingdom: national surveillance, 2006-2016. Pediatr Infect Dis J. 2019;38(10):e254-e259. doi:10.1097/INF.0000000000002368 - DOI - PubMed
    1. Agarwal HS, Latifi SQ. Streptococcus pneumoniae-associated hemolytic uremic syndrome in the era of pneumococcal vaccine. Pathogens. 2021;10(6):727. doi:10.3390/pathogens10060727 - DOI - PMC - PubMed
    1. Bertran M, Amin-Chowdhury Z, Sheppard CL, et al. . Increased incidence of invasive pneumococcal disease among children after COVID-19 pandemic, England. Emerg Infect Dis. 2022;28(8):1669-1672. doi:10.3201/eid2808.220304 - DOI - PMC - PubMed