Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2025 Mar 29:15:100328.
doi: 10.1016/j.dadr.2025.100328. eCollection 2025 Jun.

Long acting injectable buprenorphine: Perspectives from service-users, staff and stakeholders

Affiliations

Long acting injectable buprenorphine: Perspectives from service-users, staff and stakeholders

Rebecca Fish et al. Drug Alcohol Depend Rep. .

Abstract

Introduction: Long-acting injectable buprenorphine (LAIB) is a relatively novel pharmacological treatment for people with opioid dependence. Despite growing qualitative evidence, there is limited research on practitioner insights, and effectiveness of LAIB in a community setting.

Methods: Thirteen service-users (11 currently prescribed LAIB), 6 practitioners, and 4 stakeholders (public health workers) took part in semi-structured interviews (n = 23) to glean their perspectives on LAIB. They were recruited through a community drug treatment service in the NW of England. The interview schedule was informed by previous literature and co-produced with a peer worker with lived experience of drug recovery treatment. Transcripts were analysed thematically by the research team.

Results: Four major themes were identified from the interviews: A change of focus; challenges; wrap-around support; and target groups.

Discussion: Our findings support existing evidence around the individual benefits to service-users such as changes to lifestyle and reduction of stigma, as well as challenges such as the need for wrap-around support and accessible information. We found that commissioning considerations such as geographical inequalities and the need for multi-service collaboration are important in this setting.

Conclusions: LAIB treatment works well for many people in a community context that offers significant wrap-around support to service-users. The novelty of this research lies in bringing together the views of practitioners and stakeholders as well as treatment/service beneficiaries in evaluating the introduction of LAIB in a community service.

Keywords: Harm reduction; Long acting injectable buprenorphine; Opioid agonist therapy; Qualitative; Recovery.

PubMed Disclaimer

Conflict of interest statement

The authors declare the following financial interests/personal relationships which may be considered as potential competing interests: Céu Mateus reports financial support was provided by National Institute for Health and Care Research. The other authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Similar articles

References

    1. Allen E., Samadian S., Altobelli G., Johnson J., Holmwood C. Exploring patient experience and satisfaction with depot buprenorphine formulations: a mixed-methods study. Drug Alcohol Rev. 2023 - PubMed
    1. Barnett A., Savic M., Lintzeris N., Bathish R., Arunogiri S., Dunlop A.J., Haber P., Graham R., Hayes V., Lubman D.I. Tracing the affordances of long-acting injectable depot buprenorphine: a qualitative study of patients’ experiences in Australia. Drug Alcohol Depend. 2021;227 - PubMed
    1. Blackpool Council. 2019. Blackpool Drug Harm Reduction Strategy 2020-2022. Available at〈https://www.blackpooljsna.org.uk/Documents/Living-and-Working-Well/JSNA...[Accessed 01/05/2024].
    1. Blawatt S., Harrison S., Byres D., Foreman J., Amara S., Burdge W., MacDonald S., Schechter M.T., Oviedo-Joekes E. The mobilization of nurse-client therapeutic relationships in injectable opioid agonist treatment: autonomy, advocacy and action. J. Subst. Use Addict. Treat. 2023;154 - PubMed
    1. Braun V., Clarke V. Using thematic analysis in psychology. Qual. Res. Psychol. 2006;3(2):77–101.

LinkOut - more resources