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. 2025 Apr 3:15:1522992.
doi: 10.3389/fonc.2025.1522992. eCollection 2025.

Hotspots and scientometrics in gallbladder cancer surgery research: a bibliometric and visualization analysis (2014-2024)

Long-Fei Chen #  1 , Jian-Feng Bin #  2 , Qin Zhang  3 , Han Li  1 , Wei Chen  1 , Hua Ge  2
Affiliations

Hotspots and scientometrics in gallbladder cancer surgery research: a bibliometric and visualization analysis (2014-2024)

Long-Fei Chen et al. Front Oncol. .

Abstract

Background: Gallbladder cancer (GBC) is the most common malignancy of the biliary tract, with significant geographical variations in incidence. The prognosis of GBC is generally poor due to its aggressive nature and late diagnosis. Surgical resection is the only curative treatment, but less than 10% of patients are eligible for radical surgery.

Methods: This study utilized bibliometric analysis and visualization tools to analyze research trends and hotspots in GBC surgery from 2014 to 2024. Data were collected from the Web of Science Core Collection using specific search terms related to GBC and surgical methods. The analysis was performed using tools such as CiteSpace, VOSviewer, and Microsoft Excel to identify key authors, institutions, countries, and research themes.

Results: A total of 479 publications were analyzed, showing a significant increase in research output and citation frequency over the past decade. China and the United States were the leading contributors to GBC surgery research. The analysis revealed six main research clusters, focusing on early diagnosis, surgical techniques, postoperative management, and the application of advanced technologies such as laparoscopic and robotic surgery.

Conclusions: The study highlights the evolution of research priorities in GBC surgery, with a shift towards minimally invasive techniques and comprehensive postoperative management. Future research should emphasize international collaboration and the exploration of emerging technologies to improve patient outcomes.

Keywords: bibliometric analysis; gallbladder cancer; laparoscopic surgery; postoperative management; surgery.

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Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Figures

Figure 1
Figure 1
Gallbladder surgery related research into the process flow chart and ruled out.
Figure 2
Figure 2
Trends in the growth of publications and citation frequency. (A) The number of publications and citation frequency for each year from 2014 to 2024. (B) Linear prediction curves for the growth trends in publication numbers and citation frequency from 2014 to 2023.
Figure 3
Figure 3
Contributions of different countries or regions to research on gallbladder cancer surgery from 2014 to 2024. (A) The number of publications and citation counts for the top 15 countries. (B) A VOSviewer network visualization map of inter-country collaborations. (C) Collaboration networks between countries or regions.
Figure 4
Figure 4
VOSviewer visual network map of different institutions’ contributions to research on gallbladder cancer surgery.
Figure 5
Figure 5
Visual network of keywords in gallbladder cancer surgery research from 2014 to 2024. (A) Keyword clusters in gallbladder cancer surgery research. (B) Keyword visualization map of the CiteSpace network in gallbladder cancer surgery research. (C) Timeline viewer of the VOSviewer network in gallbladder cancer surgery research.
Figure 6
Figure 6
Top 25 keywords with the strongest outbreak of research related to gallbladder cancer surgery.
Figure 7
Figure 7
Treemap of the top 20 journals by publication volume in gallbladder cancer surgery research from 2014 to 2024.
See this image and copyright information in PMC

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References

    1. Sharma A, Sharma KL, Gupta A, Yadav A, Kumar A. Gallbladder cancer epidemiology, pathogenesis and molecular genetics: Recent update. World J Gastroenterol. (2017) 23:3978–98. doi: 10.3748/wjg.v23.i22.3978 - DOI - PMC - PubMed
    1. Huang J, Lucero-Prisno DE, 3rd, Zhang L, Xu W, Wong SH, Ng SC, et al. . Updated epidemiology of gastrointestinal cancers in East Asia. Nat Rev Gastroenterol Hepatol. (2023) 20:271–87. doi: 10.1038/s41575-022-00726-3 - DOI - PubMed
    1. Lazcano-Ponce EC, Miquel JF, Muñoz N, Herrero R, Ferrecio C, Wistuba II, et al. . Epidemiology and molecular pathology of gallbladder cancer. CA Cancer J Clin. (2001) 51:349–64. doi: 10.3322/canjclin.51.6.349 - DOI - PubMed
    1. Roa JC, García P, Kapoor VK, Maithel SK, Javle M, Koshiol J. Gallbladder cancer. Nat Rev Dis Primers. (2022) 8:69. doi: 10.1038/s41572-022-00398-y - DOI - PubMed
    1. Hundal R, Shaffer EA. Gallbladder cancer: epidemiology and outcome. Clin Epidemiol. (2014) 6:99–109. - PMC - PubMed

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