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. 2025 Apr 4:25:200399.
doi: 10.1016/j.ijcrp.2025.200399. eCollection 2025 Jun.

Cardiovascular risk in newly diagnosed patients with type 2 diabetes mellitus: a nationwide, facility-based, cross-sectional study in Bangladesh

A B M Kamrul-Hasan  1 , Muhammad Shah Alam  2 , Marufa Mustari  3 , Mohammad Abdul Hannan  4 , Emran Ur Rashid Chowdhury  5 , Sumon Rahman Chowdhury  6 , Md Abu Jar Gaffar  7 , Swapan Kumar Singha  8 , Choman Abdullah Mohana  9 , Ershad Mondal  9 , Md Shahinur Rahman  10 , Mohammad Motiur Rahman  11 , Sourav Sarker  12 , Md Azizul Hoque  13 , Md Rashedul Islam  14 , Md Abdul Bari Robel  15 , Shahryar Ahmad  16 , Ahmed Ifrad Bin Raunak  17 , Nur-A-Musabber  9 , Md Mostofa Kaisar  18 , Shahjada Selim  3
Affiliations

Cardiovascular risk in newly diagnosed patients with type 2 diabetes mellitus: a nationwide, facility-based, cross-sectional study in Bangladesh

A B M Kamrul-Hasan et al. Int J Cardiol Cardiovasc Risk Prev. .

Abstract

Aims: Evidence on cardiovascular (CV) risk stratification in Bangladeshi patients with type 2 diabetes mellitus (T2DM) who are asymptomatic for cardiovascular disease (CVD) is limited. This study aimed to assess the 10-year CV risk in newly diagnosed patients with T2DM.

Methods: In 2023, a cross-sectional study was carried out at endocrinology clinics in tertiary hospitals throughout Bangladesh, involving newly diagnosed patients with T2DM aged 25 to 84 who had no prior history of CVD and were asymptomatic for the condition. CV risk was assessed and classified using QRISK3.

Results: 1617 newly diagnosed patients with T2DM (age 44.92 ± 11.84 years, male 49.5 %) were analyzed. Their median QRISK3 score was 11.0 %, with 46.5 % at low, 25.7 % at moderate, and 27.8 % at high 10-year CV risk, respectively. The QRISK3 score increased with age for both men and women, with men consistently scoring higher than women in every age group. Among the age groups 25-39, 40-64, and 65-84, the percentages of patients with high 10-year CV risk were 3.3 %, 34.0 %, and 94.5 %, respectively. The median relative risk (RR) of CVD was 4.3. RR decreased with age for both sexes, and men had a lower RR than women across all age groups. A sleep duration of 6-9 h was associated with a lower 10-year CV risk.

Conclusions: Many newly diagnosed Bangladeshi patients with T2DM have substantial CV risk. QRISK3 can assist clinicians in predicting 10-year CV risk and choosing appropriate treatments to prevent CVD.

Keywords: 10-Year cardiovascular risk; QRISK3; Risk assessment; Sleep; Type 2 diabetes.

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Conflict of interest statement

The authors assert the absence of any identifiable financial conflicts or personal relationships that could be perceived as impacting the integrity of the findings reported in this manuscript.

Figures

Fig. 1
Fig. 1
Proportions of study subjects with low, moderate, and high 10-year cardiovascular risk.
Fig. 2
Fig. 2
A. Trend of median QRISK3 score with increasing age in men and women, B. Comparison of median QRISK3 score in men versus women of different age groups, C. Trend of median relative risk of CVD with increasing age in men and women, D. Comparison of median relative risk of CVD in men versus women of different age groups.
See this image and copyright information in PMC

References

    1. International Diabetes Federation . IDF Diabetes Atlas. tenth ed. 2021. https://www.diabetesatlas.org Brussels, Belgium:
    1. Volgman A.S., Palaniappan L.S., Aggarwal N.T., Gupta M., Khandelwal A., Krishnan A.V., et al. American heart association council on Epidemiology and prevention; cardiovascular disease and stroke in women and special populations committee of the council on clinical cardiology; council on cardiovascular and stroke nursing; council on quality of care and outcomes research; and stroke council. Atherosclerotic cardiovascular disease in South Asians in the United States: Epidemiology, risk factors, and treatments: a scientific statement from the American heart association. Circulation. 2018;138(1):e1–e34. doi: 10.1161/CIR.0000000000000580. - DOI - PubMed
    1. Chowdhury M.Z.I., Haque M.A., Farhana Z., Anik A.M., Chowdhury A.H., Haque S.M., et al. Prevalence of cardiovascular disease among Bangladeshi adult population: a systematic review and meta-analysis of the studies. Vasc. Health Risk Manag. 2018;14:165–181. doi: 10.2147/VHRM.S166111. - DOI - PMC - PubMed
    1. Fan W. Epidemiology in diabetes mellitus and cardiovascular disease. Cardiovasc Endocrinol. 2017;6(1):8–16. doi: 10.1097/XCE.0000000000000116. - DOI - PMC - PubMed
    1. Naito R., Miyauchi K. Coronary artery disease and type 2 diabetes mellitus. Int. Heart J. 2017;58(4):475–480. doi: 10.1536/ihj.17-191. - DOI - PubMed

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