Out-of-hospital cardiac arrest: A 10-year analysis of survival and neurological outcomes

Abstract

Background Out-of-hospital cardiac arrest (OHCA) is a major public health issue with low survival rates. Objective Identification of predictors for survival and good neurological outcomes following OHCA. Methods This retrospective study included all OHCA patients between January 2014 and December 2023. Data was collected from the local resuscitation registry and hospital electronic medical records. Neurological outcomes were measured using the Cerebral Performance Category (CPC) scale. Results At hospital admission return of spontaneous circulation (ROSC) was achieved in 36 % of cases (411/1128), with overall survival rates of 29 % (328/1128) at 24 h and 16 % (178/1128) at 30 days, respectively. Good neurological outcomes (CPC 1 and 2) were observed in 13 % (144/1128) of patients. The main suspected cause of cardiac arrest was cardiac origin (54 %, 608/1128), followed by hypoxia (11 %, 127/1128). Survivors were significantly younger (60 vs 71 years, p < 0.001), were less disabled (p < 0.001), had a higher incidence of witnessed cardiac arrest (80 % vs 69 %, p = 0.018), received more often bystander cardiopulmonary resuscitation (CPR, 62 % vs 47 %, p = 0.003) or Dispatcher Assisted-CPR (44 % vs 32 %, p = 0.004). Moreover, patients who survived at least 30 days had a higher incidence of shockable initial rhythm (57 % vs 24 %, p < 0.001). Conclusions Patients who survived at least 30 days were younger and male, had less disability, a shockable initial rhythm, and a cardiac arrest in public.

Keywords: Advanced-life-support; CPR; Cardiopulmonary resuscitation; Mortality; Outcome; Physician-staffed ambulance.