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. 2025 Aug:240:81-100.
doi: 10.1016/j.ymeth.2025.04.008. Epub 2025 Apr 17.

EffiCOVID-net: A highly efficient convolutional neural network for COVID-19 diagnosis using chest X-ray imaging

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EffiCOVID-net: A highly efficient convolutional neural network for COVID-19 diagnosis using chest X-ray imaging

Sunil Kumar et al. Methods. 2025 Aug.

Abstract

The global COVID-19 pandemic has drastically affected daily life, emphasizing the urgent need for early and accurate detection to provide adequate medical treatment, especially with limited antiviral options. Chest X-ray imaging has proven crucial for distinguishing COVID-19 from other respiratory conditions, providing an essential diagnostic tool. Deep learning (DL)-based models have proven highly effective in image diagnostics in recent years. Many of these models are computationally intensive and prone to overfitting, especially when trained on limited datasets. Additionally, conventional models often fail to capture multi-scale features, reducing diagnostic accuracy. This paper proposed a highly efficient convolutional neural network (CNN) called EffiCOVID-Net, incorporating diverse feature learning units. The proposed model consists of a bunch of EffiCOVID blocks that incorporate several layers of convolution containing (3×3) filters and recurrent connections to extract complex features while preserving spatial integrity. The performance of EffiCOVID-Net is rigorously evaluated using standard performance metrics on two publicly available COVID-19 chest X-ray datasets. Experimental results demonstrate that EffiCOVID-Net outperforms existing models, achieving 98.68% accuracy on the COVID-19 radiography dataset (D1), 98.55% on the curated chest X-ray dataset (D2), and 98.87% on the mixed dataset (DMix) in multi-class classification (COVID-19 vs. Normal vs. Pneumonia). For binary classification (COVID-19 vs. Normal), the model attains 99.06%, 99.78%, and 99.07% accuracy, respectively. Integrating Grad-CAM-based visualizations further enhances interpretability by highlighting critical regions influencing model predictions. EffiCOVID-Net's lightweight architecture ensures low computational overhead, making it suitable for deployment in resource-constrained clinical settings. A comparative analysis with existing methods highlights its superior accuracy, efficiency, and robustness performance. However, while the model enhances diagnostic workflows, it is best utilized as an assistive tool rather than a standalone diagnostic method.

Keywords: Artificial intelligence; CNN; COVID-19 detection; Deep learning; Image classification; Multi-scale features; X-ray images.

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Conflict of interest statement

Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

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