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Review
. 2025 Apr 17;21(2):240172.
doi: 10.1183/20734735.0172-2024. eCollection 2025 Apr.

The use of mechanical ventilation in interstitial lung disease

Affiliations
Review

The use of mechanical ventilation in interstitial lung disease

Timothy J Nolan et al. Breathe (Sheff). .

Abstract

This review explores the challenges and strategies for managing mechanical ventilation in interstitial lung disease (ILD), particularly during acute exacerbations. It highlights the unique physiological barriers posed by fibrotic, non-compliant lungs, discusses evidence-based approaches to noninvasive and invasive ventilation, and emphasises the importance of balancing life-sustaining treatments with palliative care. This review aims to provide practical insights into optimising respiratory support for ILD patients while aligning treatment goals with patient prognosis and preferences.

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Conflict of interest statement

Conflict of interest: P. Geoghegan reports holding a leadership role with ESICM as the National Representative for Ireland. The remaining authors have nothing to disclose.

Comment in

  • Interstitial lung diseases.
    Sulaiman I. Sulaiman I. Breathe (Sheff). 2025 Apr 17;21(2):250169. doi: 10.1183/20734735.0169-2025. eCollection 2025 Apr. Breathe (Sheff). 2025. PMID: 40257331 Free PMC article.

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