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Case Reports
. 2025 Mar 20;17(3):e80922.
doi: 10.7759/cureus.80922. eCollection 2025 Mar.

Outcome of Early Cranioplasty in Trephine Syndrome or Paradoxical Brain Herniation: A Case Report and Literature Review

Affiliations
Case Reports

Outcome of Early Cranioplasty in Trephine Syndrome or Paradoxical Brain Herniation: A Case Report and Literature Review

Zarbakhta Ashfaq et al. Cureus. .

Abstract

Sinking skin flap syndrome (SSFS) is a rare complication observed in patients after craniectomy. The intracranial pressure is decreased after craniectomy, resulting in some conditions. These include mental change, focal deficits, headache, seizures, and dysautonomia. Cranioplasty is the most commonly used treatment method for SSFS. Here, the case of a patient is presented with symptoms, including sudden loss of consciousness, aphasia, and right-side weakness. A computed tomography (CT) scan revealed hemorrhagic conversion of parietotemporal infarct with midline shift. A decompressive craniectomy was performed, and the patient developed SSFS later. Subsequently, the patient underwent cranioplasty and showed improvements in neurological deficits. SSFS is rare; only a few cases have been reported in the literature.

Keywords: cranioplasty; decompressive craniectomy; global aphasia; seizures; sinking skin flap syndrome.

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Conflict of interest statement

Human subjects: Consent for treatment and open access publication was obtained or waived by all participants in this study. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work.

Figures

Figure 1
Figure 1. Initial presentation CT brain, with the arrow representing hemorrhagic area.
Figure 2
Figure 2. CT brain post-operatively, with the arrow representing post-craniectomy changes, as mentioned in the text.
Figure 3
Figure 3. MRI T2-weighted images showing post-op changes, with the arrow pointing towards the hematoma.
Figure 4
Figure 4. CT brain, with the arrow pointing towards hygroma.
Figure 5
Figure 5. Post-cranioplasty CT brain, with the arrow representing distinct improvements of the lesion, and a decreased midline shift in the image is also appreciable.

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