A closer look: pediatric neuroimaging at 7T

Abstract

Although 7 Tesla (7T) field strength MR imaging offers higher signal-to-noise ratio and spatial resolution and improves certain types of tissue contrast, the incorporation of these systems into clinical pediatric neuroradiology has been relatively limited. Following a discussion of available hardware, current regulations, and pediatric specific safety considerations, this article briefly reviews the underlying principles behind the improved image quality attainable with certain techniques at 7T. Subsequently, specific high-performance sequences and techniques are highlighted including MP2RAGE, T2-weighted, and T2*-weighted sequences as well as MR angiography, all with sample images and comparison with standard field strengths. Finally, current clinical neuroradiological applications of 7T are explored with particular focus on focal epilepsy, multiple sclerosis, vascular diseases, and cerebral microbleeds. Ongoing and future innovations in hardware design and sequence development promise continued advancement in 7T neuroimaging and further applications to pediatric neuroradiology.

Keywords: 7 T; 7 Tesla; Magnetic resonance imaging; Neuroradiology; Pediatric; Ultra-high field.