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. 2025 Apr;38(3):1107-1108.
doi: 10.1007/s40620-025-02274-w. Epub 2025 Apr 21.

A preventable problem in pregnancy

Kareem Elbosaty  1 , Alaa Sabry  2 , Giorgina B Piccoli  2 , Rasha Shemies  3
Affiliations

A preventable problem in pregnancy

Kareem Elbosaty et al. J Nephrol. 2025 Apr.
No abstract available

Keywords: Heparin; Pregnancy; Renal tubular acidosis; Skin necrosis & thrombocytopenia.

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Conflict of interest statement

Declarations. Conflict of interests: On behalf of all authors, the corresponding author states that there are no competing interests to disclose. Ethical approval: In accordance with the guidelines and regulations pertaining to research ethics, ethical approval was not required for this study as it involved a single case and did not meet the criteria for formal ethical review. The study adhered to the principles of good research practice and the participant's rights and confidentiality were protected throughout the research process. Human and animal rights: The patient provided written/oral informed consent prior to data collection. All personal identifying information was removed from the data set. Informed consent: The patient provided written informed consent for the anonymous publication of her data and ethical clearance was not required.

Figures

Fig. 1
Fig. 1
a: extensive heparin-induced abdominal necrosis with some adjacent at-risk areas. The purple marks indicate staining by the gentian violet dye the patient purchased over-the-counter to use as an antiseptic (size 5 × 3 cm). b: recovering lesion after discontinuation of heparin and debridement
See this image and copyright information in PMC

References

    1. Schleich JM, Laurent M, Almange C (2001) Traitement par héparine chez la femme enceinte [Heparin therapy in pregnant women]. Arch Mal Coeur Vaiss 94(11 Suppl):1291–1300 (French. PMID: 11794972) - PubMed
    1. Schindewolf M, Lindhoff-Last E, Ludwig RJ, Boehncke WH (2012) Heparin-induced skin lesions. The Lancet 380(9856):1867–1879 - PubMed
    1. Schindewolf M, Gobst C, Kroll H, Recke A, Louwen F, Wolter M, Kaufmann R, Boehncke WH, Lindhoff-Last E, Ludwig RJ (2013) High incidence of heparin-induced allergic delayed-type hypersensitivity reactions in pregnancy. J Allergy Clin Immunol 132(1):131–139 - PubMed

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