Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2025 Jun 17;333(23):2108-2110.
doi: 10.1001/jama.2025.4017.

Non-Risk-Based Lung Cancer Screening With Low-Dose Computed Tomography

Affiliations

Non-Risk-Based Lung Cancer Screening With Low-Dose Computed Tomography

Caichen Li et al. JAMA. .
No abstract available

Plain language summary

This study assesses non–risk-based low-dose computed tomographic screening to assess lung cancer detection in the general population and evaluate outcomes by risk stratification.

PubMed Disclaimer

Conflict of interest statement

Conflict of Interest Disclosures: Dr C.-F. J. Yang reported consulting or advisory roles with AstraZeneca and Genentech; honoraria from AstraZeneca and Genentech; travel support from AstraZeneca; grants from the Agency for Healthcare Research and Quality (R18 HS029430-01) outside the submitted work; and serving on the board of the American Lung Cancer Screening Initiative. Ms Potter reported serving on the board of the American Lung Cancer Screening Initiative. No other disclosures were reported.

References

    1. Wood DE, Kazerooni EA, Aberle D, et al. NCCN Guidelines insights. J Natl Compr Canc Netw. 2022;20(7):754-764. doi: 10.6004/jnccn.2022.0036 - DOI - PubMed
    1. Chang GC, Chiu CH, Yu CJ, et al. ; TALENT Investigators . Low-dose CT screening among never-smokers with or without a family history of lung cancer in Taiwan. Lancet Respir Med. 2024;12(2):141-152. doi: 10.1016/S2213-2600(23)00338-7 - DOI - PubMed
    1. Yang W, Qian F, Teng J, et al. ; Written on behalf of the AME Thoracic Surgery Collaborative Group . Community-based lung cancer screening with low-dose CT in China. Lung Cancer. 2018;117(117):20-26. doi: 10.1016/j.lungcan.2018.01.003 - DOI - PubMed
    1. Chinese Thoracic Society, Chinese Medical Association; Chinese Alliance Against Lung Cancer Expert Group . Chinese expert consensus on diagnosis and treatment of pulmonary nodules (2024). Article in Chinese. Zhonghua Jie He He Hu Xi Za Zhi. 2024;47(8):716-729. doi: 10.3760/cma.j.cn112147-20231109-00300 - DOI - PubMed
    1. Jonas DE, Reuland DS, Reddy SM, et al. Screening for lung cancer with low-dose computed tomography. JAMA. 2021;325(10):971-987. doi: 10.1001/jama.2021.0377 - DOI - PubMed