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. 2025 Apr 16:20:1111-1129.
doi: 10.2147/COPD.S502971. eCollection 2025.

Recommendations for Improving Discharge-Related Care Following a COPD Exacerbation: An Expert Panel Consensus with Emphasis on Low- and Middle-Income Countries

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Recommendations for Improving Discharge-Related Care Following a COPD Exacerbation: An Expert Panel Consensus with Emphasis on Low- and Middle-Income Countries

Adrian Rendon et al. Int J Chron Obstruct Pulmon Dis. .

Abstract

Exacerbations of chronic obstructive pulmonary disease (COPD) continue to place a considerable disease and financial burden on both patients and healthcare systems, particularly in low- and middle-income countries (LMICs). Therefore, preventing future exacerbations remains a key treatment goal. However, gaps remain in the standard of COPD care following exacerbations, despite the availability of evidence-based recommendations providing guidance on discharging patients from hospital or emergency department (ED) after a COPD exacerbation. To better understand these gaps in clinical practice, an advisory board meeting of 13 international pulmonologists was convened in September 2022, with the principal objective to formulate and recommend an evidence-based hospital discharge protocol following a COPD exacerbation, with a particular focus on LMICs. Based on identified gaps in COPD care, recommendations for alleviating the burden of exacerbations were proposed, which could be delivered as a discharge protocol for implementation in hospitals and/or ED. Following a review of the available clinical evidence, including an online survey of 11 pre-meeting questions and 5 additional questions discussed during the meeting, the key unmet needs identified by the experts included poor integration of standardized protocols in routine clinical practice, failure to ensure consistent delivery of post-discharge care, and lack of efficiently functioning healthcare systems. A protocol was formulated for delivery as part of a disease management program involving an interdisciplinary approach and a care bundle, aiming to address gaps in discharge-related care by determining the likelihood of readmission and optimizing maintenance treatment plans based on assessment of symptoms and future exacerbation risk. This can provide holistic care following hospital/ED discharge and personalized treatment plans by advocating referral to a specialist. To ensure wide-ranging uptake, implementation of a discharge protocol will need to be tailored to local healthcare settings by conducting feasibility studies, standardizing clinical pathways and healthcare policies, and engaging relevant stakeholders.

Keywords: chronic obstructive pulmonary disease; discharge protocol; emergency department; exacerbation; hospital.

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Conflict of interest statement

Adrian Rendon received payment or honoraria for lectures, presentations, speaker bureaus, and manuscript writing or educational events from AstraZeneca, Chiesi, GlaxoSmithKline, and Sanofi. Susana Luhning received honorarium as speaker and travel expenses from GSK and AstraZeneca. Philip Bardin conducted educational lectures for GSK, AZ, BI, Chiesi, and Sanofi, with funds donated to a research charity (Monash Lung and Sleep Institute). Carlos Andrés Celis-Preciado received support to attend meetings, and grants, personal payment, and payment to his employer for educational and advisory work from AstraZeneca, Sanofi, and GSK that make medicines to treat COPD. Mark Cohen-Todd was a consultant and member of advisory boards for GSK, BI, and AstraZeneca, and has received honorarium as speaker and travel expenses from GSK, BI, AstraZeneca, and Luminova/Novartis. Ahmad Izuanuddin Ismail received research grant, support to attend meetings, and honoraria from AstraZeneca. Terence Seemungal received honoraria from AstraZeneca, GlaxoSmithKline, and Boehringer Ingelheim for lectures given at meetings and to attend international meetings. Nurdan Köktürk received research grant and honoraria from AstraZeneca. John R Hurst received support to attend meetings and grants and personal payment and payment to his employer for educational and advisory work from pharmaceutical companies that make medicines to treat COPD. The remaining authors report no conflicts of interest in this work.

Figures

Figure 1
Figure 1
Key gaps and unmet needs in COPD-related care and recommendations for alleviating the exacerbation-related burden.
Figure 2
Figure 2
Step-wise protocol for discharge of patients with COPD following an exacerbation.

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References

    1. World Health Organization (WHO). Chronic obstructive pulmonary disease (COPD); 2022. Available from: https://www.who.int/news-room/fact-sheets/detail/chronic-obstructive-pul...). Accessed November 14, 2023.
    1. May SM, Li JT. Burden of chronic obstructive pulmonary disease: healthcare costs and beyond. Allergy Asthma Proc. 2015;36(1):4–10. doi:10.2500/aap.2015.36.3812 - DOI - PMC - PubMed
    1. Halpin DMG, Decramer M, Celli BR, Mueller A, Metzdorf N, Tashkin DP. Effect of a single exacerbation on decline in lung function in COPD. Respir Med. 2017;128:85–91. doi:10.1016/j.rmed.2017.04.013 - DOI - PubMed
    1. Global Initiative for Chronic Obstructive Lung Disease. Global Strategy for Prevention, Diagnosis and Management of COPD; 2024. Available from: https://goldcopd.org. Accessed January 14, 2024.
    1. Anzueto A. Impact of exacerbations on COPD. Eur Respir Rev. 2010;19(116):113–118. doi:10.1183/09059180.00002610 - DOI - PMC - PubMed

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