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. 2025 Apr 22:8:0623.
doi: 10.34133/research.0623. eCollection 2025.

Engineering Cup-Shaped Nanomotors for Promoting Cell Internalization and Synergistic Tumor Therapy

Affiliations

Engineering Cup-Shaped Nanomotors for Promoting Cell Internalization and Synergistic Tumor Therapy

Ning Feng et al. Research (Wash D C). .

Abstract

Self-propulsion enzymatic nanomotors have shown tremendous potential in the field of diagnostics. In a study led by Wang and coworkers, nanoenzyme-driven cup-shaped nanomotors were designed for enhanced cell penetration and synergistic photodynamic/thermal treatments under single near-infrared laser irradiation. By combining the concepts of self-propulsion enzymatic nanomotors and synergistic dual-modal therapy, this work provides a new idea and tool for the application of nanomotors in the biomedical field.

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Conflict of interest statement

Competing interests: The authors declare that they have no competing interests.

Figures

Figure.
Figure.
The nanoenzyme-driven cup-shaped nanomotor for collaborative photodynamic/thermal therapy. PTT, photothermal therapy; PDT; photodynamic therapy.

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References

    1. Liu J, Liu J, Mu W, Ma Q, Zhai X, Jin B, Liu Y, Zhang N. Delivery strategy to enhance the therapeutic efficacy of liver fibrosis via nanoparticle drug delivery systems. ACS Nano. 2024;18(32):20861–20885. - PubMed
    1. Liu S, Yan Z, Huang Z, Yang H, Li J. Smart nanocarriers for the treatment of retinal diseases. ACS Appl Nano Mater. 2024;7(4):2070–2085. - PubMed
    1. Sanhai WR, Sakamoto JH, Canady R, Ferrari M. Seven challenges for nanomedicine. Nat Nanotechnol. 2008;3(5):242–244. - PubMed
    1. Wu L-P, Wang D, Li Z. Grand challenges in nanomedicine. Mat Sci Eng C-Mater. 2020;106: Article 110302. - PubMed
    1. Chauhan VP, Jain RK. Strategies for advancing cancer nanomedicine. Nat Mater. 2013;12(11):958–962. - PMC - PubMed

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