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Review
. 2025 Mar 5;13(3):277.
doi: 10.3390/vaccines13030277.

Advances in Chicken Infectious Anemia Vaccines

Haoqian Wang  1 , Yuqing Dan  1 , Linlin Li  1 , Xinwei Wang  1
Affiliations
Review

Advances in Chicken Infectious Anemia Vaccines

Haoqian Wang et al. Vaccines (Basel). .

Abstract

Chicken infectious anemia (CIA) is caused by the CIA virus (CIAV) and is a globally distributed immunosuppressive disease, resulting in substantial economic losses for the poultry industry. Vaccination is the most cost-effective and efficient strategy for preventing and controlling infectious diseases. The most common CIA vaccines used internationally are attenuated vaccines. Although inactivated vaccines, subunit vaccines, immune complex vaccines, recombinant live viral vector vaccines, and DNA vaccines used for preventing CIAV infection have been developed and exhibited relatively satisfactory immune responses, they have not yet achieved large-scale market applications. Therefore, accelerating the introduction of safe and effective CIA vaccines to the market and developing novel vaccines are crucial for the control of CIA in the poultry industry. This article reviews the etiological characteristics of CIAV, the epidemic features, and the research progress of CIA vaccines, and proposes future research directions, with the aim of providing innovative ideas and scientific references for the research and development of new, safe, and efficient CIA vaccines.

Keywords: CIAV; epidemic features; etiological; narrative review; vaccine.

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Conflict of interest statement

The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

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