Editorial Expression of Concern: Essential roles of PI(3)K-p110β in cell growth, metabolism and tumorigenesis

Shidong Jia^#^{1

2}, Zhenning Liu^#^{1

2}, Sen Zhang^#^{1

2}, Pixu Liu^#^{1

2}, Lei Zhang^{1

2}, Sang Hyun Lee^{1

2}, Jing Zhang^{1

2}, Sabina Signoretti^{2

3}, Massimo Loda^{2

3}, Thomas M Roberts^{4

5}, Jean J Zhao^{6

7

8}

Affiliations

¹ Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts, USA.
² Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
³ Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, USA.
⁴ Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts, USA. thomas_roberts@dfci.harvard.edu.
⁵ Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA. thomas_roberts@dfci.harvard.edu.
⁶ Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts, USA. jean_zhao@dfci.harvard.edu.
⁷ Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA. jean_zhao@dfci.harvard.edu.
⁸ Department of Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA. jean_zhao@dfci.harvard.edu.

^# Contributed equally.

PMID: 40275109
DOI: 10.1038/s41586-025-09026-7

Editorial Expression of Concern: Essential roles of PI(3)K-p110β in cell growth, metabolism and tumorigenesis

Shidong Jia et al. Nature. 2025 May.

. 2025 May;641(8062):E6.

doi: 10.1038/s41586-025-09026-7.

Authors

Affiliations

¹ Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts, USA.
² Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
³ Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, USA.
⁴ Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts, USA. thomas_roberts@dfci.harvard.edu.
⁵ Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA. thomas_roberts@dfci.harvard.edu.
⁶ Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts, USA. jean_zhao@dfci.harvard.edu.
⁷ Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA. jean_zhao@dfci.harvard.edu.
⁸ Department of Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA. jean_zhao@dfci.harvard.edu.

^# Contributed equally.

PMID: 40275109
DOI: 10.1038/s41586-025-09026-7

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Expression of concern for

Essential roles of PI(3)K-p110beta in cell growth, metabolism and tumorigenesis.
Jia S, Liu Z, Zhang S, Liu P, Zhang L, Lee SH, Zhang J, Signoretti S, Loda M, Roberts TM, Zhao JJ. Jia S, et al. Nature. 2008 Aug 7;454(7205):776-9. doi: 10.1038/nature07091. Epub 2008 Jun 25. Nature. 2008. PMID: 18594509 Free PMC article.

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Editorial Expression of Concern: Essential roles of PI(3)K-p110β in cell growth, metabolism and tumorigenesis

Affiliations

Editorial Expression of Concern: Essential roles of PI(3)K-p110β in cell growth, metabolism and tumorigenesis

Authors

Affiliations

Expression of concern for

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