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Review
. 2025 Apr 1;10(4):214.
doi: 10.3390/biomimetics10040214.

Myoelectric Control in Rehabilitative and Assistive Soft Exoskeletons: A Comprehensive Review of Trends, Challenges, and Integration with Soft Robotic Devices

Affiliations
Review

Myoelectric Control in Rehabilitative and Assistive Soft Exoskeletons: A Comprehensive Review of Trends, Challenges, and Integration with Soft Robotic Devices

Alejandro Toro-Ossaba et al. Biomimetics (Basel). .

Abstract

Soft robotic exoskeletons have emerged as a transformative solution for rehabilitation and assistance, offering greater adaptability and comfort than rigid designs. Myoelectric control, based on electromyography (EMG) signals, plays a key role in enabling intuitive and adaptive interaction between the user and the exoskeleton. This review analyzes recent advancements in myoelectric control strategies, emphasizing their integration into soft robotic exoskeletons. Unlike previous studies, this work highlights the unique challenges posed by the deformability and compliance of soft structures, requiring novel approaches to motion intention estimation and control. Key contributions include critically evaluating machine learning-based motion prediction, model-free adaptive control methods, and real-time validation strategies to enhance rehabilitation outcomes. Additionally, we identify persistent challenges such as EMG signal variability, computational complexity, and the real-time adaptability of control algorithms, which limit clinical implementation. By interpreting recent trends, this review highlights the need for improved EMG acquisition techniques, robust adaptive control frameworks, and enhanced real-time learning to optimize human-exoskeleton interaction. Beyond summarizing the state of the art, this work provides an in-depth discussion of how myoelectric control can advance rehabilitation by ensuring more responsive and personalized exoskeleton assistance. Future research should focus on refining control schemes tailored to soft robotic architectures, ensuring seamless integration into rehabilitation protocols. This review is a foundation for developing intelligent soft exoskeletons that effectively support motor recovery and assistive applications.

Keywords: electromyography; exoskeletons; motion intention estimation; myoelectric control; soft robotics.

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Conflict of interest statement

The authors declare no conflicts of interest.

Figures

Figure 1
Figure 1
Word cloud summarizing the key themes and concepts explored in this review. The most frequent terms highlight key concepts related to soft robotic exoskeletons, myoelectric control, and rehabilitation strategies.
Figure 2
Figure 2
Soft robotics rehabilitation and assistance exoskeletons. (a) Bowden cable-driven soft exoskeleton [51]. (b) CADEL (CAble Driven device for Elbow assistance) soft exoskeleton [50]. (c) Suit-type shape-memory alloy (SMA) soft exoskeleton [30].
Figure 3
Figure 3
Myoelectric control scheme.
Figure 4
Figure 4
Myoelectric control research.
Figure 5
Figure 5
Sliding window technique. WL corresponds to the window length, WInc to the window increment, and tp to the processing time of the EMG motion intention estimation algorithm.
Figure 6
Figure 6
Comparison of control strategies in exoskeletons.
Figure 7
Figure 7
Trends in soft robotics exoskeleton publications from 2012 to 2024.
Figure 8
Figure 8
Challenges in myoelectric control.

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