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. 2025 Apr 25;25(1):492.
doi: 10.1186/s12884-025-07573-5.

Development of an intervention for smoking cessation in pregnant women using a theory-based approach

Estelle Clet  1   2 , Adrianna Burtin  3   4 , Nolwenn Stevens  3   4 , Charlotte Kervran  4 , Rebecca Ratel  3   4 , Manon Vergneau  4 , Perrine Moysan  4 , Manon Frevol  3 , Loïc Sentilhes  5 , Philippe Castera  6 , François Alla  3   4 ; 5A-QUIT-N groupx
Collaborators, Affiliations

Development of an intervention for smoking cessation in pregnant women using a theory-based approach

Estelle Clet et al. BMC Pregnancy Childbirth. .

Abstract

Background: While the global prevalence of smoking during pregnancy is 1.7%, it rises to 8.1% in Europe, where it is the main modifiable risk factor for morbidity and mortality during pregnancy. However, pregnancy is a key time to implement smoking cessation interventions, as women are more likely to adopt health-promoting behaviours during this period. Despite the availability of resources (e.g. policies, tools) and strategies (e.g. nicotine replacement therapy) to address smoking, their implementation remains neither optimal nor systematic. To address this, a multi-disciplinary multi-professional team developed the 5A-QUIT-N intervention to promote smoking cessation in pregnant women, by mobilising health professionals and optimising existing resources. Rather than creating new resources, the intervention uses existing tools and strategies and better integrates them into the pregnancy monitoring process. This article describes the development and operationalisation of the 5A-QUIT-N intervention.

Methods: The development of the 5A-QUIT-N intervention involved three stages. First, its components were established according to national recommendations and a final list was validated by a scientific committee. Next, obstacles and levers that could influence their implementation and effectiveness were identified through a scoping review and semi-structured interviews. The resulting data were then used to design the first version of the intervention.

Results: Findings from the literature and field experiences highlighted the need for better mobilisation and coordination of the existing resources. The 5A-QUIT-N intervention was developed to address these issues by improving resource organisation within each region. At the clinical level, it aims to enhance healthcare professionals' skills in smoking cessation practices using existing resources. At the organisational level, it promotes closer coordination between perinatal and smoking cessation professionals. The involvement of local stakeholders and local resources is an integral part of the intervention, as these vary from one region to another.

Conclusion: This intervention was made possible thanks to the combination of a literature search, a qualitative study, and commitment from stakeholders from grassroots level upwards.

Keywords: Evidence-based health promotion; Health promotion; Innovation; Pregnancy; Smoking cessation; Theory-based; Tobacco.

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Conflict of interest statement

Declarations. Ethics approval and consent to participate: This study received a favourable recommendation from the Research Ethics Committee of the University Hospital of Bordeaux. The recommendation has the following reference: CER-BDX 2024–15. For the interviews, oral consent was obtained from all participants, depending on the nature of the data (opinions on existing or potential interventions). The Research Ethics Committee of the University Hospital of Bordeaux approved this procedure. Consent for publication: Not applicable. Competing interests: The authors declare no competing interests.

Figures

Fig. 1
Fig. 1
Flow chart of methodology
Fig. 2
Fig. 2
Organisation of the 5 A-QUIT-N intervention
See this image and copyright information in PMC

References

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