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Editorial
. 2025 Apr 7;18(4):538.
doi: 10.3390/ph18040538.

Trends and Pitfalls in the Progress of Network Pharmacology Research on Natural Products

Alexander Panossian  1
Affiliations
Editorial

Trends and Pitfalls in the Progress of Network Pharmacology Research on Natural Products

Alexander Panossian. Pharmaceuticals (Basel). .

Abstract

Herbs, used as food and a source of medicine for centuries, have been extensively studied over time for their chemical and pharmacological properties, with two main aims [...].

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Conflict of interest statement

Author Alexander Panossian is self-employed at the independent R&D company Phytomed AB. The author declares that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

References

    1. Panossian A., Lemerond T., Efferth T. State-of-the-art review on botanical hybrid preparations in phytomedicine and phytotherapy research: Background and perspectives. Pharmaceuticals. 2024;17:483. doi: 10.3390/ph17040483. - DOI - PMC - PubMed
    1. Panossian A., Lemerond T., Efferth T. Adaptogens in Long-Lasting Brain Fatigue: An Insight from Systems Biology and Network Pharmacology. Pharmaceuticals. 2025;18:261. doi: 10.3390/ph18020261. - DOI - PMC - PubMed
    1. Panossian A., Seo E.J., Efferth T. Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology. Phytomed. Int. J. Phytother. Phytopharm. 2018;50:257–284. doi: 10.1016/j.phymed.2018.09.204. - DOI - PubMed
    1. Panossian A., Seo E.J., Wikman G., Efferth T. Synergy assessment of fixed combinations of Herba Andrographidis and Radix Eleutherococci extracts by transcriptome-wide microarray profiling. Phytomedicine. 2015;22:981–992. doi: 10.1016/j.phymed.2015.08.004. - DOI - PubMed
    1. Panossian A., Efferth T. Network Pharmacology of Adaptogens in the Assessment of Their Pleiotropic Therapeutic Activity. Pharmaceuticals. 2022;15:1051. doi: 10.3390/ph15091051. - DOI - PMC - PubMed

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