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Comparative Study
. 1985 Jul;4(7):759-66.
doi: 10.3109/02713688509020031.

Corneal endothelial changes in diabetic dogs

R W Yee, M Matsuda, T S Kern, R L Engerman, H F Edelhauser
Comparative Study

Corneal endothelial changes in diabetic dogs

R W Yee et al. Curr Eye Res. 1985 Jul.

Abstract

The corneal endothelium of alloxan diabetic dogs was examined by wide-field specular microscopy and compared to that of age-matched non-diabetic dogs. Computer-assisted morphometry of individual cells showed that the diabetic dog endothelium had marked polymegethism and pleomorphism similar to that previously described in diabetic patients. There also appeared to be a positive correlation between the degree of these endothelial changes and the diabetic control as demonstrated by HbA1 concentration.

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