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. 2025 Aug;81(4):3162-3169.
doi: 10.1177/10519815251329231. Epub 2025 Apr 28.

Physical activity and sedentariness levels in patients with post-exertional malaise resulting from post-COVID-19 syndrome

Affiliations

Physical activity and sedentariness levels in patients with post-exertional malaise resulting from post-COVID-19 syndrome

Kamel-Eddine Elkebir et al. Work. 2025 Aug.

Abstract

BackgroundPost-exertional malaise (PEM) is a complex phenomenon characterized by extreme fatigue, reduced endurance, and muscular and joint pains. Physical activity (PA) has recognized health benefits, including reducing the risks of chronic diseases and mortality. During the pandemic, a general decline in PA was measured, but the profile of the various components of PA and sedentariness in patients with PEM resulting from post-COVID-19 syndrome (PCS-19) remains scarce. It is relevant to observe the impact of these discomforts on PQ after their occurrence.ObjectiveThis study examines the detailed PA and sedentary profile of individuals affected by PEM associated with PCS-19.MethodsAn online questionnaire disseminated via social media platform evaluated PA and sedentariness before and after COVID-19 diagnostic.ResultsIndividuals with PEM (n = 154) became more sedentary and inactive post-COVID-19. Specifically, PA at work decreased in women and those whose last infection occurred over a year ago. Walk decreased for women but increased for men. Bike journeys generally decreased after COVID-19. The severity of PEM, the pace of recovery, and fear of malaise influenced PA changes.ConclusionsThe PCS-19 leads to increased sedentary behavior and a decline in PA, particularly at work, and is more pronounced among women and those more severely affected by PEM. These findings are critical for post-COVID PA resumption, including for workers who go back to work and who regain normal duties while being potentially deconditioned.

Keywords: bike; infection; sedentary behavior; sex; walk; workers.

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Conflict of interest statement

Conflicting interestsThe authors declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

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