Lung tissue penetration of temocillin
- PMID: 4029020
- DOI: 10.2165/00003495-198500295-00031
Lung tissue penetration of temocillin
Abstract
Eight patients about to have the whole or part of a lung resected were given a 2g bolus dose of temocillin. A series of serum samples and a piece of peripheral lung tissue were collected and assayed for temocillin concentration. 30 minutes after drug administration, the mean serum and tissue concentrations were 172 mg/L and 45 mg/kg respectively.
Similar articles
-
Temocillin concentrations in human tissues.Drugs. 1985;29 Suppl 5:167-70. doi: 10.2165/00003495-198500295-00034. Drugs. 1985. PMID: 3928320 Clinical Trial.
-
Quantification of temocillin biliary excretion and gallbladder bile concentration in healthy subjects.Drugs. 1985;29 Suppl 5:146-50. doi: 10.2165/00003495-198500295-00030. Drugs. 1985. PMID: 4029019 Clinical Trial.
-
Temocillin penetration of peripheral lymph.Drugs. 1985;29 Suppl 5:114-7. doi: 10.2165/00003495-198500295-00024. Drugs. 1985. PMID: 4029013
-
Temocillin: lymph penetration and protein binding.Int J Clin Pharmacol Ther Toxicol. 1990 Jul;28(7):286-91. Int J Clin Pharmacol Ther Toxicol. 1990. PMID: 2201651
-
Temocillin revived.J Antimicrob Chemother. 2009 Feb;63(2):243-5. doi: 10.1093/jac/dkn511. Epub 2008 Dec 18. J Antimicrob Chemother. 2009. PMID: 19095679 Review.
Cited by
-
Pharmacodynamics of Temocillin in Neutropenic Murine Infection Models.Antimicrob Agents Chemother. 2023 Feb 16;67(2):e0143322. doi: 10.1128/aac.01433-22. Epub 2023 Jan 24. Antimicrob Agents Chemother. 2023. PMID: 36692307 Free PMC article.
-
Pharmacokinetics and Pharmacodynamics of Temocillin.Clin Pharmacokinet. 2018 Mar;57(3):287-296. doi: 10.1007/s40262-017-0584-7. Clin Pharmacokinet. 2018. PMID: 28849402 Review.
References
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources