Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2025 Apr;41(4):1047-1051.
doi: 10.12669/pjms.41.4.9828.

Effect of 18F-FDG PET/CT Imaging Combined with 3D-Printed Templates on Biopsy Efficacy in Patients with Lung Tumor

Jianyang Zhang  1 , Cheng Ran  2 , Jing Chen  3 , Huimin Song  4 , Xianbo Li  5
Affiliations

Effect of 18F-FDG PET/CT Imaging Combined with 3D-Printed Templates on Biopsy Efficacy in Patients with Lung Tumor

Jianyang Zhang et al. Pak J Med Sci. 2025 Apr.

Abstract

Objective: To investigate the effect of 18F-FDG PET/CT imaging combined with 3D-printed templates on the biopsy results and diagnostic efficacy in patients with lung tumors.

Methods: This was a comparative study. A total of 80 patients with suspected lung tumors admitted to Baoding NO.1 Central Hospital from May 2022 to December 2023 were selected as the research subjects and divided into the study group and the control group per different detection methods. Patients in the control group were treated with 18F-FDG PET/CT imaging-guided percutaneous aspiration biopsy of the lung, while those in the observation group underwent 18F-FDG PET/CT imaging-guided percutaneous aspiration biopsy of the lung combined with 3D printed templates. Afterward, the biopsy results of the two groups and their diagnostic efficacy and complications were compared.

Results: No significant differences were observed in tissue length and scanning time between the two groups (P>0.05). The operation time and number of biopsies in the observation group were less than those in the control group, with significant differences (P<0.05). Meanwhile, there was no statistically significant difference in specificity (15.00% vs. 27.50%) and misdiagnosis rate (2.50% vs. 10.00%) between the two groups (P>0.05). Moreover, the incidence of complications in the observation group was 5.00%, lower than the control group (7.50%), with no statistically significant differences (χ²=0.213, P=0.644).

Conclusion: The observation group was found to have superior effect than control group, with fewer punctures and shorter puncture time, making it worthy of promotion in clinical application.

Keywords: 18F-FDG; 3D-Printed Templates; Diagnostic Efficacy; Lung; PET/CT; Percutaneous Aspiration Biopsy.

PubMed Disclaimer

Conflict of interest statement

Conflicts of interest: None.

Similar articles

See all similar articles

References

    1. Jiao J, Li WW, Shang YH, Li XF, Jiao M. Clinical effects of Chemotherapy combined with Immunotherapy in patients with advanced NSCLC and the effect on their nutritional status and immune function. Pak J Med Sci. 2023;39(2):404–408. doi:10.12669/pjms.39.2.6365. - PMC - PubMed
    1. Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I, Jemal A, et al. Global Cancer Statistics 2020:GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries. CA Cancer J Clin. 2021;71(3):209–249. doi:10.3322/caac.21660. - PubMed
    1. Kuzucuoglu M, Gokyer A, Kula O, Yekdes AC, Sunal BS, Karamustafaoglu YA, et al. Relationship between the Size and Location of the Mass and Hilar and Mediastinal Lymph Node Metastasis in Early and Locally Advanced Non-Small Cell Lung Cancer. J Coll Physicians Surg Pak. 2020;30(2):172–176. doi:10.29271/jcpsp.2020.02.172. - PubMed
    1. Di Capua D, Bracken-Clarke D, Ronan K, Baird AM, Finn S. The Liquid Biopsy for Lung Cancer:State of the Art, Limitations and Future Developments. Cancers (Basel) 2021;13(16):3923. doi:10.3390/cancers13163923. - PMC - PubMed
    1. Sun XY, Chen TX, Chang C, Teng HH, Xie C, Ruan MM, et al. SUVmax of 18FDG PET/CT Predicts Histological Grade of Lung Adenocarcinoma. Acad Radiol. 2021;28(1):49–57. doi:10.1016/j.acra.2020.01.030. - PubMed

LinkOut - more resources