Myths and Facts Regarding Low-Carbohydrate Diets
- PMID: 40292478
- PMCID: PMC11944661
- DOI: 10.3390/nu17061047
Myths and Facts Regarding Low-Carbohydrate Diets
Abstract
As the prevalence of chronic diseases persists at epidemic proportions, health practitioners face ongoing challenges in providing effective lifestyle treatments for their patients. Even for those patients on GLP-1 agonists, nutrition counseling remains a crucial strategy for managing these conditions over the long term. This paper aims to address the concerns of patients and practitioners who are interested in a low-carbohydrate or ketogenic diet, but who have concerns about its efficacy, safety, and long-term viability. The authors of this paper are practitioners who have used this approach and researchers engaged in its study. The paper reflects our opinion and is not meant to review low-carbohydrate diets systematically. In addressing common concerns, we hope to show that this approach has been well researched and can no longer be seen as a "fad diet" with adverse health effects such as impaired renal function or increased risk of heart disease. We also address persistent questions about patient adherence, affordability, and environmental sustainability. This paper reflects our perspective as clinicians and researchers engaged in the study and application of low-carbohydrate dietary interventions. While the paper is not a systematic review, all factual claims are substantiated with citations from the peer-reviewed literature and the most rigorous and recent science. To our knowledge, this paper is the first to address potential misconceptions about low-carbohydrate and ketogenic diets comprehensively.
Keywords: diabetes; heart disease; ketogenic; low-carbohydrate diet; obesity.
Conflict of interest statement
M.C. has received travel compensation for his service on the Abbott Freestyle Libre Advisory Board; D.H.G. received honoraria from Blue Cross Blue Shield of Michigan for running a statewide obesity summit and from the National Kidney Foundation of Michigan for work related to diabetes prevention. M.G. is the founder and CEO of OwnaHealth, a company that treats diabetes and obesity; K.J.-Z. is the founder and Medical Director of Trajectory Health Partners; T.K. is an unpaid member of the Board of Directors of the Society of Metabolic Health Practitioners, and his spouse has an ownership interest in Rosette’s, a food company; J.V. is a co-founder and shareholder of Virta Health, serves as a science advisor for Simply Good Foods and Nutrishus Brands, and has authored books that recommend a ketogenic diet; all other authors report no conflicts of interest.
References
-
- Goldenberg J.Z., Day A., Brinkworth G.D., Sato J., Yamada S., Jönsson T., Beardsley J., Johnson J.A., Thabane L., Johnston B.C. Efficacy and Safety of Low and Very Low Carbohydrate Diets for Type 2 Diabetes Remission: Systematic Review and Meta-analysis of Published and Unpublished Randomized Trial Data. BMJ. 2021;372:m4743. doi: 10.1136/bmj.m4743. - DOI - PMC - PubMed
-
- Kazeminasab F., Miraghajani M., Khalafi M., Sakhaei M.H., Rosenkranz S.K., Santos H.O. Effects of Low-carbohydrate Diets, With and Without Caloric Restriction, on Inflammatory Markers in Adults: A Systematic Review and Meta-analysis of Randomized Clinical Trials. Eur. J. Clin. Nutr. 2024;78:569–584. doi: 10.1038/s41430-024-01431-x. - DOI - PubMed
-
- Davies M.J., D’Alessio D.A., Fradkin J., Kernan W.N., Mathieu C., Mingrone G., Rossing P., Tsapas A., Wexler D.J., Buse J.B. Management of Hyperglycemia in Type 2 Diabetes, 2018. A Consensus Report by the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD) Diabetes Care. 2018;41:2669–2701. doi: 10.2337/dci18-0033. - DOI - PMC - PubMed
Publication types
MeSH terms
Substances
Grants and funding
LinkOut - more resources
Full Text Sources
Research Materials
