A Plea for a Genetics-First Approach in Arrhythmogenic Cardiomyopathies

Affiliations

¹ Departments of Cardiology (A.S.J.M.t.R., R.N.W.H.), University Medical Center Utrecht, The Netherlands.
² Genetics (J.P.v.T.), University Medical Center Utrecht, The Netherlands.

Editorial

Anneline S J M Te Riele et al. Circulation. 2025.

. 2025 Apr 29;151(17):1231-1234.

doi: 10.1161/CIRCULATIONAHA.125.074022. Epub 2025 Apr 28.

¹ Departments of Cardiology (A.S.J.M.t.R., R.N.W.H.), University Medical Center Utrecht, The Netherlands.
² Genetics (J.P.v.T.), University Medical Center Utrecht, The Netherlands.

No abstract available

Keywords: Editorials; arrhythmia; cardiomyopathy; death, sudden; diagnosis; gene; genetics; management, clinical.

Conflict of interest statement

None.

Natural History and Clinical Outcomes of Patients With DSG2/DSC2 Variant-Related Arrhythmogenic Right Ventricular Cardiomyopathy.
Chen L, Hu Y, Saguner AM, Bauce B, Liu Y, Shi A, Guan F, Chen Z, Bueno Marinas M, Wu L, Foltran D, Hermida A, Fressart V, Pinci S, Celeghin R, Chen Z, Zhang B, Lin Y, Liu X, Cason M, Martini M, Rigato I, Brunckhorst C, Biller R, Basso C, Yang B, Zhao X, Cadrin-Tourigny J, Gasperetti A, James CA, Zhou X, Gandjbakhch E, Pilichou K, Duru F, Hu S. Chen L, et al. Circulation. 2025 Apr 29;151(17):1213-1230. doi: 10.1161/CIRCULATIONAHA.124.072226. Epub 2025 Mar 24. Circulation. 2025. PMID: 40123482