[Steady potential dynamics in hypothalamic structures in response to a tolerogen and an immunogen]
- PMID: 4029436
[Steady potential dynamics in hypothalamic structures in response to a tolerogen and an immunogen]
Abstract
DC potential shifts due to induction of immune tolerance and immune memory were studied in hypothalamic structures. The lost capability of immune cooperation after tolerogen administration was accompanied by a monophasic negative shift of DC potential. Immunogen administration induced a positive shift of DC potential within 1-3 days. An immunogen fraction induced a pyrogenic response. There seems to be a correlation between the pyrogenic and immunogenic actions of antigens and the reorganization of hypothalamic neurons function.