Dose Effect of Antithymocyte Globulin or Post-transplant Cyclophosphamide in Haploidentical Peripheral Blood Stem Cell Transplantation: A Comparative Study

Yosuke Nakaya¹, Hirohisa Nakamae², Hideki Nakasone³, Hiroshi Okamura¹, Naonori Harada⁴, Koji Kawamura⁵, Seitaro Terakura⁶, Yuta Hasegawa⁷, Tetsuya Eto⁸, Takahiro Fukuda⁹, Nobuhiro Hiramoto¹⁰, Koji Nagafuji¹¹, Shuichi Ota¹², Yumiko Maruyama¹³, Toshiro Kawakita¹⁴, Ken-Ichi Matsuoka¹⁵, Noriko Doki¹⁶, Tomohiko Kamimura¹⁷, Toshihiko Ando¹⁸, Takashi Akasaka¹⁹, Yoshiko Atsuta²⁰, Junya Kanda²¹

Affiliations

¹ Department of Hematology, Osaka Metropolitan University Graduate School of Medicine, Osaka, Japan.
² Department of Hematology, Osaka Metropolitan University Graduate School of Medicine, Osaka, Japan. Electronic address: hirohisa@omu.ac.jp.
³ Division of Hematology, Jichi Medical University Saitama Medical Center, Saitama, Japan; Division of Emerging Medicine for Integrated Therapeutics, Center for Molecular Medicine, Jichi Medical University, Shimotsuke, Japan.
⁴ Department of Hematology, Osaka Metropolitan University Graduate School of Medicine, Osaka, Japan; Department of Hematology, Fuchu Hospital, Osaka, Japan.
⁵ Department of Multidisciplinary Internal Medicine, Division of Clinical Laboratory Medicine, Tottori University, Tottori, Japan.
⁶ Department of Hematology and Oncology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
⁷ Department of Hematology, Hokkaido University Hospital, Sapporo, Japan.
⁸ Department of Hematology, Hamanomachi Hospital, Fukuoka, Japan.
⁹ Department of Hematopoietic Stem Cell Transplantation, National Cancer Center Hospital, Tokyo, Japan.
¹⁰ Department of Hematology, Kobe City Medical Center General Hospital, Kobe, Japan.
¹¹ Department of Medicine, Division of Hematology and Oncology, Kurume University Hospital, Kurume, Japan.
¹² Department of Hematology, Sapporo Hokuyu Hospital, Sapporo, Japan.
¹³ Department of Hematology, University of Tsukuba Hospital, Tsukuba, Japan.
¹⁴ Department of Hematology, NHO Kumamoto Medical Center, Kumamoto, Japan.
¹⁵ Department of Hematology and Oncology, Okayama University Hospital, Okayama, Japan.
¹⁶ Hematology Division, Tokyo Metropolitan Cancer and Infectious Diseases Center, Komagome Hospital, Tokyo, Japan.
¹⁷ Department of Hematology, Harasanshin Hospital, Fukuoka, Japan.
¹⁸ Department of Internal Medicine, Faculty of Medicine, Division of Hematology, Respiratory Medicine and Oncology, Saga University, Saga, Japan.
¹⁹ Department of Hematology, Tenri Hospital, Tenri, Japan.
²⁰ Japanese Data Center for Hematopoietic Cell Transplantation, Nagoya, Japan; Department of Registry Science for Transplant and Cellular Therapy, Aichi Medical University School of Medicine, Nagakute, Japan.
²¹ Department of Hematology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.

PMID: 40294821
DOI: 10.1016/j.jtct.2025.04.007

Dose Effect of Antithymocyte Globulin or Post-transplant Cyclophosphamide in Haploidentical Peripheral Blood Stem Cell Transplantation: A Comparative Study

Yosuke Nakaya et al. Transplant Cell Ther. 2025 Aug.

. 2025 Aug;31(8):544.e1-544.e5.

doi: 10.1016/j.jtct.2025.04.007. Epub 2025 Apr 26.

Authors

Affiliations

¹ Department of Hematology, Osaka Metropolitan University Graduate School of Medicine, Osaka, Japan.
² Department of Hematology, Osaka Metropolitan University Graduate School of Medicine, Osaka, Japan. Electronic address: hirohisa@omu.ac.jp.
³ Division of Hematology, Jichi Medical University Saitama Medical Center, Saitama, Japan; Division of Emerging Medicine for Integrated Therapeutics, Center for Molecular Medicine, Jichi Medical University, Shimotsuke, Japan.
⁴ Department of Hematology, Osaka Metropolitan University Graduate School of Medicine, Osaka, Japan; Department of Hematology, Fuchu Hospital, Osaka, Japan.
⁵ Department of Multidisciplinary Internal Medicine, Division of Clinical Laboratory Medicine, Tottori University, Tottori, Japan.
⁶ Department of Hematology and Oncology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
⁷ Department of Hematology, Hokkaido University Hospital, Sapporo, Japan.
⁸ Department of Hematology, Hamanomachi Hospital, Fukuoka, Japan.
⁹ Department of Hematopoietic Stem Cell Transplantation, National Cancer Center Hospital, Tokyo, Japan.
¹⁰ Department of Hematology, Kobe City Medical Center General Hospital, Kobe, Japan.
¹¹ Department of Medicine, Division of Hematology and Oncology, Kurume University Hospital, Kurume, Japan.
¹² Department of Hematology, Sapporo Hokuyu Hospital, Sapporo, Japan.
¹³ Department of Hematology, University of Tsukuba Hospital, Tsukuba, Japan.
¹⁴ Department of Hematology, NHO Kumamoto Medical Center, Kumamoto, Japan.
¹⁵ Department of Hematology and Oncology, Okayama University Hospital, Okayama, Japan.
¹⁶ Hematology Division, Tokyo Metropolitan Cancer and Infectious Diseases Center, Komagome Hospital, Tokyo, Japan.
¹⁷ Department of Hematology, Harasanshin Hospital, Fukuoka, Japan.
¹⁸ Department of Internal Medicine, Faculty of Medicine, Division of Hematology, Respiratory Medicine and Oncology, Saga University, Saga, Japan.
¹⁹ Department of Hematology, Tenri Hospital, Tenri, Japan.
²⁰ Japanese Data Center for Hematopoietic Cell Transplantation, Nagoya, Japan; Department of Registry Science for Transplant and Cellular Therapy, Aichi Medical University School of Medicine, Nagakute, Japan.
²¹ Department of Hematology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.