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Review
. 2025 Jul;49(13):3736-3749.
doi: 10.1007/s00266-025-04855-3. Epub 2025 Apr 28.

Global Analysis and Latest Research Hot Spots of Lipoedema/Lipodystrophy Investigation and Management: A Bibliometric Analysis and Visualized Review

Ammar Alsayegh  1 , Ziyad Alsuwilem  2 , Abdullah Alsalem  2 , Abdullah Alanzan  2 , Rasha Alashjaee  3 , Maryam Almuslem  4 , Obai Raffah  5 , Rahaf Almutairi  6 , Khalid Arab  7
Affiliations
Review

Global Analysis and Latest Research Hot Spots of Lipoedema/Lipodystrophy Investigation and Management: A Bibliometric Analysis and Visualized Review

Ammar Alsayegh et al. Aesthetic Plast Surg. 2025 Jul.

Abstract

Background: Lipodystrophy presents clinical management challenges due to its varied expression and low incidence. Despite the clinical importance, there has been no systematic evaluation of the research output in terms of geographical distribution, institutional contributions, or emerging trends. This study aims to fill that gap by conducting a comprehensive bibliometric analysis of the global research landscape on lipodystrophy.

Methods: Utilizing the Web of Science core collection, studies from 2010 to 2024 were analyzed. Bibliometric indicators were processed using VOSviewer to identify trends through graphical co-occurrence mapping.

Results: A total of 826 studies from 57 countries were included. The USA led with 259 publications (30.51%). The most productive institutions were the National Institute of Diabetes and Digestive and Kidney Diseases with 43 publications (14.98%). Among 166 journals, the Journal of Clinical Endocrinology and Metabolism had the highest publications (43, 25.90%) and citations per publication (58). The most co-cited article was The Diagnosis and Management of Lipodystrophy Syndromes (2016), which was referenced 290 times.

Conclusion: This analysis highlights research trends and collaborative networks, areas for future investigation, and identifies the gaps and emerging trends that will inform future research directions.

No level assigned: This journal requires that authors assign a level of evidence to each submission to which Evidence-Based Medicine rankings are applicable. This excludes Review Articles, Book Reviews, and manuscripts that concern Basic Science, Animal Studies, Cadaver Studies, and Experimental Studies. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .

Keywords: Bibliometric; Citation analysis; Collaboration network; Lipodystrophy; Lipoedema; Liposuction.

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Conflict of interest statement

Declarations. Conflict of interest: The authors declare that they have no conflicts of interest to disclose Human and Animal Rights: This article does not contain any studies with human participants or animals performed by any of the authors Informed Consent: For this type of study, informed consent is not required.

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References

    1. Araújo-Vilar D, Santini F. Diagnosis and treatment of lipodystrophy: a step-by-step approach. J Endocrinol Invest. 2019;42(1):61–73. https://doi.org/10.1007/s40618-018-0887-z . - DOI
    1. Carvalho R. Lipedema: a common though often unrecognized condition. Chin J Plast Reconstr Surg. 2024;6(3):149–53. https://doi.org/10.1016/j.cjprs.2024.06.005 . - DOI
    1. Melvin A, Stears A, Savage DB. Recent developments in lipodystrophy. Curr Opin Lipidol. 2019;30(4):284–90. https://doi.org/10.1097/MOL.0000000000000613 . - DOI
    1. Krüger P, Hartinger R, Djabali K. Navigating lipodystrophy: insights from laminopathies and beyond. Int J Mol Sci. 2024;25(15):8020. https://doi.org/10.3390/ijms25158020 . - DOI
    1. Brown RJ, Araujo-Vilar D, Cheung PT, et al. The diagnosis and management of lipodystrophy syndromes: a multi-society practice guideline. J Clin Endocrinol Metab. 2016;101(12):4500–11. https://doi.org/10.1210/jc.2016-2466 . - DOI

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