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Review
. 2025 Sep 1;68(3):448-452.
doi: 10.1097/GRF.0000000000000926. Epub 2025 Apr 29.

In-utero Therapy for Fetal Aqueductal Stenosis

Stephen P Emery  1 , Stephanie Greene  2 , Youngjae Chun  3 , Tiffany E Deihl  1 , Nika M Hazen  1
Affiliations
Review

In-utero Therapy for Fetal Aqueductal Stenosis

Stephen P Emery et al. Clin Obstet Gynecol. .

Abstract

Advances in prenatal diagnosis, bioengineering, and minimally invasive surgical techniques have led investigators to reconsider in-utero therapy for fetal aqueductal stenosis, a form of congenital hydrocephalus that has been held under a moratorium since the 1980s. This article will review the definition, history, prenatal diagnosis, contemporary management, and future directions in clinical and basic science research for in-utero intervention for fetal aqueductal stenosis.

Keywords: congenital hydrocephalus; fatal aqueductal stenosis; fetal intervention; prenatal diagnosis.

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References

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